Results 101 to 110 of about 9,837,127 (264)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Multi-Instrument Observations of the Ionospheric Response Caused by the 8 April 2024 Total Solar Eclipse

Remote Sensing
This paper investigates ionospheric response characteristics from multiple perspectives based on globally distributed GNSS data and products, ionosonde data, FORMOSAT-7/COSMIC-2 occultation data, and Swarm satellite observations caused by the total solar
Hui Zhang, Ting Zhang, Xinyu Zhang, Yunbin Yuan, Yifan Wang, Yutang Ma   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

How Do Collaborative Approaches Shape Power Dynamics in Therapeutic Relationships? Evidence From Recovery‐Oriented Mental Health Services

Health Expectations
Introduction Recovery‐oriented mental health services emphasise collaboration, empowerment and service‐user involvement. However, less is known about how power is enacted within relationships described as collaborative.
Elena Faccio, Michele Rocelli, Lorenzo Binaggia, Elisa Giolli, Diego Romaioli, Giacomo Chiara, Claudio Agostini, Roberto Vitelli, Ludovica Aquili   +8 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Does a Citizen Science Approach Enhance the Effectiveness of Flood Early Warning Systems? Evidence from the Akaki Catchment, Ethiopia

Citizen Science: Theory and Practice
Flooding has emerged as a significant concern in the Akaki catchment area of Ethiopia, affecting settlements and properties. Early warning systems (EWSs) are implemented to reduce flood risks, but power dynamics among at-risk communities and stakeholders
Likimyelesh Nigussie, Tilaye Worku Bekele, Alemseged Tamiru Haile, Anna Mdee, Alan Nicol, Joshua Cohen, Charity Osei-Amponsah, Hailay Zeray Tedla, Kirubel Demissie   +8 more
doaj   +1 more source

Three-way interaction effect of entrepreneurial orientation, CEO power, and organizational slack on Indonesian firms’ performance [PDF]

Problems and Perspectives in Management
This study aims to explore the complex interplay between entrepreneurial orientation, CEO power, and organizational slack, and their collective impact on firm performance within Indonesia’s manufacturing sector, providing actionable insights to optimize ...
Ida Ayu Kartika Maharani, Alfina Alfina, Fajar Destari, Ali Mujahidin, Faizatul Hiqmah, Indrianawati Usman   +5 more
doaj   +1 more source

Unfolding the Twitter scene of the 2017 UEFA Champions League Final: social media networks and power dynamics

European Sport Management Quarterly, 2018
Research question: This study investigated the Twitter networks of the Champions League hashtag (#UCL) across the 2017 UEFA Champions League Final. Through an examination of network parameters and shifting structures, the analyses disclosed patterns of ...
Grace Yan, N. Watanabe, S. Shapiro, M. Naraine, Kevin Hull   +4 more
semanticscholar   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Revisiting the patriarchal bargain: The intergenerational power dynamics of household money management in rural Nepal

World Development, 2018
Highlights • We analyzed the intergenerational power dynamics of money management in rural households in contemporary Nepal.• We found that junior wives and husbands often became secret allies in seeking financial autonomy from their in-laws ...
L. Gram, J. Skordis-Worrall, J. Mannell, D. Manandhar, N. Saville, J. Morrison   +5 more
semanticscholar   +1 more source