ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
The SPA-cube framework: An integrated approach for analysing power dynamics in environmental governance. [PDF]
Sahide MAK +5 more
europepmc +1 more source
Situating Biomedical and Professional Monopoly at the Intersections of Structural, Ideational and Agentic Power Comment on "Power Dynamics Among Health Professionals in Nigeria: A Case Study of the Global Fund Policy Process". [PDF]
Kapilashrami A.
europepmc +1 more source
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source
Understanding the influence of power dynamics in intersectoral collaboration: A realist evaluation in Assam, India. [PDF]
Aivalli P +3 more
europepmc +1 more source
Power Dynamics Among Health Professionals in Nigeria: A Case Study of the Global Fund Policy Process. [PDF]
Lassa S +4 more
europepmc +1 more source
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Relationship Power Dynamics and Financial Dependence Among Sexual Minority Men in Relationships: Associations With Intimate Partner Violence. [PDF]
Choo S +3 more
europepmc +1 more source
Examining power dynamics in global health governance using topic modeling and network analysis of Twitter data. [PDF]
Bermudez GF, Prah JJ.
europepmc +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source

