Results 101 to 110 of about 715,335 (264)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Numerical Simulation and Process Optimization of Laser Welding in 6056 Aluminum Alloy T-Joints

open access: yesCrystals
This paper conducts a numerical simulation of the laser welding process for 6056 aluminum alloy stringers and skin T-joints using Simufact Welding. Initially, the accuracy of the finite element simulation is validated, followed by an exploration of the ...
Jin Peng   +10 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Optimization of wind-solar-hydrogen gas turbine complementary system configuration based on MOPSO algorithm

open access: yesReli fadian
To meet the urgent need for enhanced grid regulation capabilities due to the high penetration of renewable energy and to resolve load-source imbalances, the optimization configuration method for a wind-solar-hydrogen gas turbine complementary system is ...
WANG Yaping   +4 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Power-efficiency constraint for chemical motors

open access: yesPhysical Review E
Chemical gradients provide the primordial energy for biological functions by driving the mechanical movement of microscopic engines. Their thermodynamic properties remain elusive, especially concerning the dynamic change in energy demand in biological systems.
R. X. Zhai, Hui Dong
openaire   +3 more sources

Commission problems and countermeasures of integrated membrane technology in boiler make-up water system of a power plant

open access: yesGongye shui chuli
Based on the technical renovation project of boiler make-up water system in a power plant in North China,the design characteristics and operation mode of ultrafiltration-first stage reverse osmosis-second stage reverse osmosis-electrodeionization(EDI ...
ZHANG Kai   +6 more
doaj   +1 more source

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