Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Novel modeling strategy for a BCI set-up applied in an automotive application: an industrial way to use EM simulation tools to help Hardware and ASIC designers to improve their designs for immunity tests [PDF]
Electronics suppliers of automotive industry use BCI (Bulk Current Injection) measurements to qualify immunity robustness of their equipment whereas electronics components manufacturers use DPI (Direct Power Injection) to qualify immunity of their ...
Chernobryvko, Mykola +5 more
core
Adaptive reference model predictive control for power electronics [PDF]
An adaptive reference model predictive control (ARMPC) approach is proposed as an alternative means of controlling power converters in response to the issue of steady-state residual errors presented in power converters under the conventional model ...
Hui, SY, Tan, SC, Yang, Y
core +1 more source
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
Non-Contact Methods for High-Voltage Insulation Equipment Diagnosis during Operation
The article describes a complex of non-contact methods for remote diagnosis of high-voltage insulators as well as the two-channel method for remote diagnostics of the operating state of high-voltage insulators, based on the registration of partial ...
Dmitry A. Ivanov +4 more
doaj +1 more source
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
Smart transformer/large flexible transformer
Solid-state transformer-based smart transformer (ST) can provide the dc connectivity and advanced services to improve the grid performance and to increase the penetration of the power electronics interfaced resources (e.g., distributed generators and ...
Rongwu Zhu +3 more
doaj +1 more source
The power electronics industry is undergoing a revolution driven by an industry 4.0 perspective, with smart and green/hybrid energy management systems being the requirement of the future.
Preeti Warrier, Pritesh Shah
doaj +1 more source
Diamond semiconductor technology for RF device applications [PDF]
This paper presents a comprehensive review of diamond electronics from the RF perspective. Our aim was to find and present the potential, limitations and current status of diamond semiconductor devices as well as to investigate its suitability for RF ...
Davidson, Jimmy L. +4 more
core +1 more source
FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee +7 more
wiley +1 more source

