Results 51 to 60 of about 625,205 (219)
CONCEPTS OF IMPROVING CURRENT PROTECTION OF POWER-GRID LINES
The 6–35 kV power-grid current protection serves to protect the transmission lines against phase-to-phase short-circuits. The major disadvantage of it lies in the relatively large time delays of the last stages especially in the main sections ...
F. A. Romaniuk, M. A. Shevaldin
doaj
Real-Time Co-Simulation of Electric Machines Using Unity and Simulink for Laboratory Applications
The demand for hybrid learning rose during the past few years, especially in the post-COVID-19 pandemic era, where on campus education was significantly impacted, particularly laboratory courses, due to the loss of hands-on experience. In response, there
Fatima M. Badreddine +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
The paper considers a new algorithm for formation of orthogonal components of input values in microprocessor relay protection of power lines in distribution networks.
F. A. Romaniuk, M. A. Shevaldin
doaj
The Substantiation of Priority Directions for the Structural and Technological Modernization of the Electricity Generation Sector [PDF]
The article substantiates the necessity of the structural and technological modernization of the electricity generation sector of Ukraine in view of the promising directions of technological development of modern energy and the production sufficiency of ...
Kyzym Mykola O. +2 more
doaj
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
The active development of the mobile platforms sector such as smartphones, smart watches, fitness bracelets and other wearable electronic devices in the last 4 years has caused a huge growth of the market of mobile applications-services.
M. I. Fursanov, P. A. Sazonov
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source

