Results 51 to 60 of about 3,756,482 (348)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Multi-objective optimization algorithm for economy and flexibility of cogeneration unit with heat storage

open access: yes电力工程技术
With the sustained growth of renewable energy, the flexibility of the power system has emerged as a critical indicator, influenced by frequent peak regulation.
WANG An   +5 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Theoretical Investigation of the Formation Mechanism of NH3 and HCN during Pyrrole Pyrolysis: The Effect of H2O

open access: yesMolecules, 2018
Coal is a major contributor to the global emission of nitrogen oxides (NOx). The NOx formation during coal utilization typically derives from the thermal decomposition of N-containing compounds (e.g., pyrrolic groups).
Ji Liu   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Multi-scene application of intelligent inspection robot based on computer vision in power plant

open access: yesScientific Reports
As industries develop, the automation and intelligence level of power plants is constantly improving, and the application of patrol robots is also increasingly widespread.
Lulu Lin, Jianxian Guo, Lincheng Liu
doaj   +1 more source

Research on operational flexibility and energy consumption characteristics of cogeneration considering primary network heat transfer constraints

open access: yesFrontiers in Energy Research
High back pressure cogeneration units demonstrate superior energy utilization efficiency, but their operation is significantly influenced by primary network water temperature and flow rate.
Cheng Sun   +5 more
doaj   +1 more source

Optimal Distributed Power Generation Under Network-Load Constraints [PDF]

open access: yes, 2010
In electrical power networks nowadays more and more customers are becoming power-producers, mainly because of the development of novel components for decentralized power generation (solar panels, small wind turbines and heat pumps).
Bloemhof, G, Bosman, J, van den Akker, M
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Spectrophotovoltaic orbital power generation [PDF]

open access: yes
A subscale model of a photovoltaic power system employing spectral splitting and 1000:1 concentration was fabricated and tested. The 10-in. aperture model demonstrated 15.5% efficiency with 86% of the energy produced by a GaAs solar cell and 14% of the ...
Carroll, J., Knowles, G.
core   +4 more sources

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