Results 51 to 60 of about 360,817 (268)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Design and Performance Study of SOFC-"GT+ST" System Based on Hydrogen Fuel
[Objective] For the oxygen ion conductive solid fuel cell fueled by hydrogen, the paper proposed a SOFC-"GT+ST" system with the cathode and anode of the fuel cell entering the gas turbine and steam turbine respectively, and analyzed the impact of ...
Yunrui CHENG +5 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Performance improvement of straight darrieus type wind turbine by cylindrical guide
In late years, from the viewpoints of drying up of fossil fuels such as oil or coal, and prevention of global warming, the renewable energy such as solar power generation or wind power generation attracts attention. The wind power generation can generate
Kiyoshi KAWAGUCHI, Yukihiro HARUYAMA
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The present study performed a system-level simulation model for poly-generation applications, based on gasification technology with the commercial chemical process simulator, Pro/II® V8.1.1.
P.C. Chen, H.M. Chiu, Y.P. Chyou
doaj +1 more source
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Hydrodynamic Development and Optimisation of a Retrofittable Dual-Mode Propeller Turbine
Dual-mode propellers, as propulsion and turbine devices, have found widespread application in renewable energy systems for marine vehicles, particularly in sailing boats and yachts.
Joylan Rao Erriah +2 more
doaj +1 more source
Curtailment in a Highly Renewable Power System and Its Effect on Capacity Factors
The capacity factor of a power plant is the ratio of generation over its potential generation. It is an important measure to describe wind and solar resources.
Alexander Kies +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

