Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Regionalized Generation Expansion Planning: Integrating Spatial Constraints
A typical power system consists of a network of generation, transmission, and load spanning a wide area, with varying spatial characteristics crucial for realistic problem-solving.
Radhanon Diewvilai +1 more
doaj +1 more source
Multiport power electronics circuitry for integration of renewable energy sources in low power applications : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Electrical Engineering at Massey University, Palmerston North, New Zealand [PDF]
The increasing demand for electricity and the global concern about environment has led energy planners and developers to explore and develop clean energy sources.
Rehman, Zubair
core
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah +7 more
wiley +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim +3 more
wiley +1 more source
Reliability management of power systems with wind power generation and energy storage [PDF]
With increasing concerns of sustainable development of energy resources, many countries have planned to incorporate large percentages of renewable energy into their electrical power systems. Wind energy draws most attentions because it can be produced at acceptable cost with relatively mature technologies.
openaire +2 more sources
International audienceThe purpose of this work is the analysis of the uncertainties affecting an electric transmission network with wind power generation and their impact on its reliability. A stochastic model was developed to simulate the operations and
Golea, L. R. +3 more
core +3 more sources
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu +11 more
wiley +1 more source

