Results 31 to 40 of about 142,337 (263)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Reliability Evaluation Method for Independent Small Offshore Electric Systems

Energies, 2021
As an independent power system, the reliability of offshore electric system is closely related to the smooth progress of offshore oil production. There are two major characteristics of this type of power system.
Jun Guan, Wei Du, Xiuli Wang, Xianjue Luo, Xingyang Liu, Xue Li   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

LLM-Powered Benchmark Factory: Reliable, Generic, and Efficient

Proceedings of the 64th Annual Meeting of the Association for Computational Linguistics (Volume 1: Long Papers)
The rapid advancement of large language models (LLMs) has led to a surge in both model supply and application demands. To facilitate effective matching between them, reliable, generic and efficient benchmark generators are widely needed. However, human annotators are constrained by inefficiency, and current LLM benchmark generators not only lack ...
Peiwen Yuan, Shaoxiong Feng, Yiwei Li 0001, Xinglin Wang, Yueqi Zhang, Jiayi Shi, Chuyi Tan, Boyuan Pan, Yao Hu 0002, Kan Li 0001   +9 more
openaire   +3 more sources

Risk assessment of electric power generation systems using modified jellyfish search algorithm

TESEA, Transactions on Energy Systems and Engineering Applications
An electric utility's main goal is to fulfil the requirements and expectations of its customers by providing power. When there are uncertainties, like equipment failures, system reliability evaluation offers a framework to guarantee that the system will
Archana Chittari, Y.V. Sivareddy, V. Sankar   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Multi-Objective Reservoir Optimization Balancing Energy Generation and Firm Power

Energies, 2015
To maximize annual power generation and to improve firm power are important but competing goals for hydropower stations. The firm power output is decisive for the installed capacity in design, and represents the reliability of the power generation when ...
Fang-Fang Li, Jun Qiu
doaj   +1 more source

Operating Reliability Evaluation of Power Systems With Demand-Side Resources Considering Cyber Malfunctions

IEEE Access, 2020
Demand-side resources (DSRs) have been shown to be valuable for providing reserve capacity and enhancing the reliability of power systems with high wind power penetration.
Heping Jia, Changzheng Shao, Dunnan Liu, Chanan Singh, Yi Ding, Yanbin Li   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source