Results 71 to 80 of about 922,509 (295)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Integrating the PV-Diesel Hybrid System for Reliability Improvement in Distribution System

JAREE (Journal on Advanced Research in Electrical Engineering), 2019
In Myanmar, as the main power generation is hydro power generation. the utility cannot supply sufficient power to customers during the dry season. Besides interruptions occur frequently due to aging system and lack of prospered protection.
cho cho myint, Ohn Zin Lin, Soe Soe Ei Aung   +2 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Techno-Economic analysis of distributed generation for power system reliability and loss reduction

International Journal of Sustainable Energy, 2023
This paper presents a techno-economic analysis of the impact of distributed generation (DG) integration for power loss reduction and reliability of two 33 kV radial outgoing feeders at the Motta distribution substation in Ethiopia. Transient earth faults
Bimrew Mhari Enyew, Ayodeji Olalekan Salau, Baseem Khan, Issaias Gidey Hagos, Haymanot Takele, Oluwafunso Oluwole Osaloni   +5 more
doaj   +1 more source

Survey of aircraft electrical power systems [PDF]

, 1972
Areas investigated include: (1) load analysis; (2) power distribution, conversion techniques and generation; (3) design criteria and performance capabilities of hydraulic and pneumatic systems; (4) system control and protection methods; (5) component and
Brandner, J. J., Lee, C. H.
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Composite System Reliability Evaluation With Essential Reliability Services Assessment of Wind Power Integrated Power Systems

IEEE Open Access Journal of Power and Energy, 2020
With the increasing penetration of renewable resources and the retirements of conventional coal-fired generation units, power systems are undergoing significant transformation with the instantaneous renewable generation penetration sometimes approaching ...
Yingying Wang, Vijay Vittal, Mojdeh Khorsand, Chanan Singh   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Risk analysis of power systems for both real and reactive power

Journal of Modern Power Systems and Clean Energy, 2013
With the high penetration of renewable energy sources, the reliability of power systems becomes more vulnerable than ever because of the greater uncertainty and intermittence in power generation. Reactive power plays an important role in the power system
Wenping Qin, Peng Wang, Xiaoqing Han, Fanhua Meng   +3 more
doaj   +1 more source

Multiport power electronics circuitry for integration of renewable energy sources in low power applications : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Electrical Engineering at Massey University, Palmerston North, New Zealand [PDF]

, 2017
The increasing demand for electricity and the global concern about environment has led energy planners and developers to explore and develop clean energy sources.
Rehman, Zubair
core