Results 51 to 60 of about 15,166 (267)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Least loss contract in deregulated power system using relative electrical distance (RED) concept

Journal of Electrical Systems and Information Technology, 2018
In the earlier vertically integrated power system, the mechanism of competitive transmission pricing did not exist because of circumscribed utilization of power within a territory.
P.K. Hota, A.P. Naik
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Evolutionary Generator Maintenance Scheduling in Power Systems

, 2007
No
Dahal, Keshav P., Galloway, S.J.
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A Joint Optimization Approach on Monthly Balancing Mechanism and Unit Maintenance Scheduling

IEEE Access
In the Chinese electricity market, the deviation between monthly actual electricity demand and generation plans has become particularly prominent amidst deepening power system reform. This study focuses on the uncertainties of wind power and photovoltaic
Zhang Huie, Liu Dagui, Yin Shaowu, Wang Weiqing, Bai Caiqing, Zhang Huimin   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Time-Triggered Task Offloading Scheduling in TSN-Based Edge Computing Power Networks

IEEE Access
Computing power networks (CPN), connecting distributed computing resources over networks, have been proposed as potential next-generation novel network systems to enable optimal resource allocation among multiple computing nodes.
Hongrui Nie, Yang Wu, Weifeng Zhu, Jinzuo Zhong, Hang Yang, Yu Zhou   +5 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

An Optimization Method for Day-Ahead Generation Interval of Cascade Hydropower Adapting to Multi-Source Coordinated Scheduling Requirements

Energies
Multi-source coordinated scheduling has become the predominant operational paradigm in power systems. However, substantial differences among hydropower, thermal power, wind power, and photovoltaic sources in terms of response speed, regulation capability,
Shushan Li, Chonghao Li, Huijun Wu, Zhipeng Zhao, Huan Wang, Yongxi Kang, Chuntian Cheng, Changhong Li   +7 more
doaj   +1 more source