Results 41 to 50 of about 372,404 (290)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

A graph neural network enhanced decision transformer for efficient optimization in dynamic smart charging environments

Energy and AI
Electric-vehicle smart charging requires quick decision-making under uncertainty while enforcing strict electricity grid and user requirements. Mathematical optimization becomes too slow at scale, while online reinforcement learning struggles with sparse
Stavros Orfanoudakis, Nanda Kishor Panda, Peter Palensky, Pedro P. Vergara   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Selection of an IGCT for multilevel converters dedicated to high‐voltage direct current grid connection of offshore wind‐farms

IET Power Electronics, 2021
Grid connection of remote offshore wind‐parks uses high‐voltage direct current technology and in order to reduce costs and losses and maximise profitability, semiconductor power losses must be minimised.
Davin Guedon, Philippe Ladoux, Sébastien Sanchez, Sébastien Cornet, Thomas Stiasny, Christian Winter   +5 more
doaj   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Assessing Oscillatory Stability With Dominant Grid-Forming Power Systems for Active Power Imbalances

IEEE Open Access Journal of Power and Energy
As the integration of renewable energy accelerates, ensuring power system stability becomes increasingly critical. This research utilized a Root Mean Square (RMS) synthetic model of the future 380 kV Dutch power system towards 2050 to analyze its ...
Sander Lid Skogen, Jose Luis Rueda Torres   +1 more
doaj   +1 more source

Community-Owned Solar Power and Micro Grids for New York State [PDF]

, 2018
This policy brief discusses how community owned solar projects and micro grids offer a sustainable alternative to reliance on the large power grid and polluting fossil fuels. It explains how micro grids work and looks at how they are connected to and can
Yovanoff, David
core   +1 more source

Superfluid turbulence from quantum Kelvin wave to classical Kolmogorov cascades

, 2009
A novel unitary quantum lattice gas algorithm is used to simulate quantum turbulence of a BEC described by the Gross-Pitaevskii equation on grids up to 5760^3.
A. N. Kolmogorov, George Vahala, Jeffrey Yepez, Linda Vahala, Min Soe, R. J. Donnelly, R. P. Feynman   +6 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Bounds and Estimates for the Response to Correlated Fluctuations in Asymmetric Complex Networks

, 2021
We study the spreading of correlated fluctuations through networks with asymmetric and weighted coupling. This can be found in many real systems such as renewable power grids. These systems have so far only been studied numerically.
Auer, Sabine, Hellmann, Frank, Kurths, Jürgen, Plietzsch, Anton   +3 more
core