Results 91 to 100 of about 13,304,558 (343)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Measuring the spectral running from cosmic microwave background and primordial black holes

, 2018
We constrain the spectral running by combining cosmic microwave background (CMB) data, baryon acoustic oscillation (BAO) data and the constraint from primordial black holes (PBHs).
Huang, Qing-Guo, Li, Jun
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Kiloparsec-scale star formation law in M81 and M101 based on AKARI far-infrared observations

, 2010
We assess the relationships between the surface densities of the gas and star formation rate (SFR) within spiral arms of the nearby late-type spiral galaxies M81 and M101. By analyzing these relationships locally, we derive empirically a kiloparsec scale
Allen, Bigiel, Brouillet, Calzetti, Chynoweth, Cottrell, Cox, Dale, de Jong, Draine, Elmegreen, Freedman, Gao, Garnett, Gordon, Gordon, H. Kaneda, H. Shibai, Hamajima, Hasegawa, Hildebrand, Kaufman, Kawada, Kenney, Kennicutt, Kennicutt, Kennicutt, Knapen, Li, Lin, Maddalena, Misiriotis, Murakami, Parker, Pilyugin, Prescott, Pérez-González, Rice, Rieke, Rogstad, Rots, Sandage, Santillán, Sauvage, Schmidt, Schuster, Scoville, Scoville, Shirahata, Siebenmorgen, Smith, Suzuki, Suzuki, T. Nakagawa, T. Onaka, T. Suzuki, Taniguchi, Van der Hulst, Wilson   +58 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Matroid designs of prime power index

Journal of Combinatorial Theory, Series A, 1978
AbstractA class of BIBD's is constructed with parameters generalizing those of the finite projective geometries. These designs are used to construct matroids in which the hyperplanes are equicardinal and the complement of every hyperplane has prime power cardinality.
Kestenband, Barbu C, Peyton Young, H
openaire   +2 more sources

A Simplified Model for Approximating “World Power Index (WPI)” [PDF]

Amfiteatru Economic
Modern societies are characterized by an intensive interaction among participants to socialeconomic life, with a large literature being consecrated to the evaluation of the competitive capacity of the market-players. Both the micro-level of this complex
Emilian Dobrescu
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Comprehensive evaluation of power quality for coal mine power supply system

Gong-kuang zidonghua, 2017
In view of power quality problem caused by progressively increase of nonlinear devices of coal mine enterprise, evaluation index and comprehensive evaluation method of coal mine power quality were proposed.
WANG Shenghua
doaj   +1 more source