Results 111 to 120 of about 13,304,558 (343)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

The primordial "f_NL" non-Gaussianity, and perturbations beyond the present horizon

, 2009
We show a primordial non-linear "f_NL" term may produce unphysically large CMB anisotropy for a red-tilted primordial power spectrum ...
Andrew R. Liddle, European Space Agency, J. Clavel, Jaiseung Kim, Pavel Naselsky, Scott Dodelson, Viatcheslav Mukhanov, W H. Press   +7 more
core   +1 more source

Novel parameters for predicting fluid responsiveness during the mini fluid challenge and ability of the cardiac power index: an observational cohort study. [PDF]

Turk J Med Sci, 2023
Abdullah T, Gökduman HC, Enişte İA, Atasever AG, Ali A, Gümüş Özcan F.   +5 more
europepmc   +1 more source

International organisation analysed with the power index method [PDF]

, 2005
The period of globalisation has seen more and more of international and regional organisation. Setting up an organisation with a group of state entails a resolution to the following two questions: (1) How are votes to be allocated?
Lane, Jan-Erik
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

An EigenFactor-weighted power mean generalization of the Euclidean Index.

PLoS ONE, 2019
This paper proposes a weighted generalization of the recently developed Euclidean Index. The weighting mechanism is designed to reflect the reputation of the journal within which an article appears.
M Ryan Haley
doaj   +1 more source

Relationship between power strength and anaerobic power index as a clear picture of the effect of strength training among young soccer elite players

Слобожанський науково-спортивний вісник, 2019
Purpose: muscle contraction has both mechanical to produce movement and metabolic properties to produce energy. However, manipulation of strength training planes (horizontal or vertical) subject to be an important training strategy to develop soccer ...
Mohammed Zerf, Mohamed Arab. Kerroum , Bouabdellah S.B.A.   +2 more
doaj   +1 more source

Determination of the extent of dissection in early gastric cancer based on lymph node station power index. [PDF]

BJS Open, 2022
Jeon CH, Park KB, Kim S, Seo HS, Kim IH, Song KY, Lee HH.   +6 more
europepmc   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source