Results 91 to 100 of about 1,866,984 (300)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Analysis on Energy Saving of 350 MW Supercritical Turbine with Low-Grade Energy Heating Technology
Zhongguo dianli, 2019 The extraction of steam for heat supply in traditional combined heat and power generation plant is found with several issues such as low heating capacity, large power loss, high comprehensive energy consumption and low exergy efficiency.
Guoqiang ZHOU, Xianming SUN
doaj +1 more source
Antineutrino flux from the Laguna Verde Nuclear Power Plant [PDF]
, 2015 We present a calculation of the antineutrino flux produced by the reactors at the Laguna Verde Nuclear Power Plant in M\'exico, based on the antineutrino spectra produced in the decay chains of the fission fragments of the main isotopes in the reactor ...
Aguilar-Arevalo, Alexis A. +1 more
core +3 more sources
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A Novel Hybrid-Fuel Storage System of Compressed Air Energy for China
Energies, 2014 Compressed air energy storage (CAES) is a large-scale technology that provides long-duration energy storage. It is promising for balancing the large-scale penetration of intermittent and dispersed sources of power, such as wind and solar power, into ...
Wenyi Liu +6 more
doaj +1 more source
Electric Power Generation from Solar Photovoltaic Technology: Is It Marketable in Pakistan? [PDF]
Solar photovoltaic systems are prohibitively expensive in terms of installation costs. Power from them is also available intermittently—only when energy from the sun is available.
A. H. Nayyar +2 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Numerical simulation study of novel air-cooled condenser with lateral air supply
Case Studies in Thermal Engineering, 2019 Uneven distribution of internal temperature and air flow field are considered to be the essential defects of the Λ-frame air-cooled condenser (ΛACC) in a power plant.
Yu Zhou +3 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Energies, 2019 Apart from electric vehicles, most internal combustion (IC) engines are powered while burning petroleum-based fossil or alternative fuels after mixing with inducted air.
Kaushal Nishad +3 more
doaj +1 more source