Results 51 to 60 of about 387,504 (252)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Study of SOF2 adsorption properties on α-Al2O3(0 0 0 1) surface based on density functional theory

open access: yesDiscover Applied Sciences
SOF2 as one of the two typical partial discharge decomposition components of SF6 gas insulation medium, not only accelerates equipment lifespan reduction but also poses toxic and harmful environmental pollution risks.
Lijiang Ma   +7 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Numerical and Experimental Modelling of a Wave Energy Converter Pitching in Close Proximity to a Fixed Structure

open access: yesJournal of Marine Science and Engineering, 2019
Free-floating bodies are commonly modelled using Cummins’ equation based on linear potential flow theory and including non-linear forces when necessary.
Pilar Heras   +3 more
doaj   +1 more source

Power plant engineering handbooks.

open access: yes, 1923
v. 1 Boilers, furnaces and boiler accessories.--v. 2 Piping for power and heating plants.--v. 3 Power plant electrical equipment.--v. 4 Refrigeration plant equipment.--v.
Power plant engineering.
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Power plant.

open access: yes, 1917
Mode of access: Internet.Merged with Practical engineer, to form: Power plant engineering, in Sept ...

core  

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