Results 81 to 90 of about 827,554 (312)
The expressive power of the shuffle product
Information and Computation, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Berstel, J +4 more
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Power law in hadron production
Physics Letters B, 2001 significantly revised version to appear in Phys.
Gaździcki, Marek, Gorenstein, Mark I.
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Modeling of Ethiopian Wind Power Production Using ERA5 Reanalysis Data
, 2021 Ethiopia has huge wind energy potential. In order to be able to simulate the power system operation, hourly time series of wind power is needed. These can be obtained from ERA5 data but first a realistic model is needed.
Mengesha Mamo +7 more
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Operational costs induced by fluctuating wind power production in Germany and Scandinavia
, 2008 Adding wind power generation in a power system changes the operational patterns of the existing units due to the variability and partial predictability of wind power production.
Brand, H. +7 more
core +1 more source
, 2021 Ice formation on a wind turbine alters the airfoil profiles of the blades and causes degradation in the aerodynamic performance of the wind turbine and the resulting power production losses.
Tuncer, Ismail H. +5 more
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source