Results 51 to 60 of about 9,125,519 (306)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Journal of Engineering, 2019 The network reconfiguration of a vessel power system (VPS) is one of the most important approaches to restore its power supply and improve its survivability.
Qingsong Yan +3 more
doaj +1 more source
A review of waste heat recovery from the marine engine with highly efficient bottoming power cycles
, 2020 This paper aims at presenting an extensive review of waste heat recovery (WHR) from the marine engine with highly efficient bottoming power cycles which include the steam Rankine cycle, organic Rankine cycle, Kalina cycle and CO2-based power cycles ...
Sipeng Zhu, Kunyi Zhang, K. Deng
semanticscholar +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Features of calculating the temperature field in an annular porous layer under infinite heating
Известия высших учебных заведений: Проблемы энергетикиTo date, easily recoverable oil reserves have already been extracted, so deposits with residual oil reserves or places with weak permeability are of great interest.
N. D. Yakimov +3 more
doaj +1 more source
JAMA Surgery, 2019 Importance Enhanced Recovery After Surgery (ERAS) care has been reported to be associated with improvements in outcomes after colorectal surgery compared with traditional care.
J. Ripollés-Melchor +13 more
semanticscholar +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Temperature field in a cylindrical porous layer during “endless” heating with heat outflow
Известия высших учебных заведений: Проблемы энергетикиRELEVANCE. This article proposes a mathematical model for calculating the temperature field in the annular porous layer of an downhole reactor during continuous heating of a bottomhole zone containing high-viscosity oil (VVN) and natural bitumen (PB ...
N. D. Yakimov +3 more
doaj +1 more source