Results 71 to 80 of about 5,027,539 (269)
We derive a simple error estimate for equally spaced, polynomial interpolation of power series that does not require the uniform bounds on derivatives of the Cauchy remainder. The key steps are expressing Newton coefficients in terms of Stirling numbers S(i, j) of the second kind and applying the concavity of ln S(i, j).
openaire +2 more sources
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The paper discusses a nonlinear parabolic equation describing the process of heat conduction for the case of the power dependence of the heat conductivity factor on temperature.
A. Kazakov, L. F. Spevak, O. A. Nefedova
doaj
Exact Parametric and Semi-Analytical Solutions for the Rucklidge-Type Dynamical System
The behavior of the Rucklidge-type dynamical system was investigated, providing some semi-analytical solutions, in this paper. This system was analytically investigated by means of the Optimal Auxiliary Functions Method (OAFM) for two cases.
Remus-Daniel Ene +2 more
doaj +1 more source
APPLICATIONS AND DEVELOPMENT OF A NEW VOLTERRA SCHEME FOR SOLVING NONLINEAR INTEGRAL EQUATIONS [PDF]
Volterra integral equations (VIEs) are extensively utilized across scientific, technological and engineeringdisciplines for modeling systems influenced by past behaviors or interactions.
Ishaq A.A. +3 more
doaj +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
An Improved Analytical Approximation of the Bessel Function J2(x)
In this paper, we derive an analytical and explicit approximation for the Bessel function J2(x) for positive real x with a maximum absolute error of approximately 0.004, which refines some new published analytic approximation.
Mansour Mahmoud, Hanan Almuashi
doaj +1 more source
THE MODEL OF THE RADIAL-THRUST BALL BEARING FOR ANALYSIS OF NONLINEAR VIBRATIONS OF THE ROTOR [PDF]
The non-linear model of resilient forces of pre-loaded ball bearing is developed. The contact forces are obtained and arranged in the Heyn’s row on the basis of Herts theory.
S. Filipkovskyi
doaj
Power series expansions of arbitrary order functional difference equations [PDF]
This paper looks at some real and complex generalizations of power series associated with some arbitrary order functional difference equations considered as generalizations and extensions of Fibonacci and Lucas numbers.
Anthony G. Shannon +2 more
doaj +1 more source

