Results 61 to 70 of about 1,054,431 (346)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
IEEE Access, 2019 The low-harmonic and high-power density multi-pulse autotransformer has many advantages, such as simple structure, high reliability, high efficiency, strong overload ability, and so on.
Yingying Zhang +4 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Overview of circuit topologies for inductive pulsed power supplies
CES Transactions on Electrical Machines and Systems, 2017 The pulsed power supply (PPS) is one important component in the electromagnetic launch system. The inductive PPSs have attracted researchers’ attentions with the major advantages of high energy storage density (over the capacitive PPSs) as well as simple
Xinjie Yu, Xukun Liu
doaj +1 more source
Simplified power supplies for ion thrusters [PDF]
The initial development and demonstration of power supplies with an order of magnitude reduction in parts count, leading to increased reliability at lower weight, while still maintaining thrust system performance are discussed.
Gruber, R. P.
core +1 more source
Stability analysis of electric power systems for ‘more electric’ aircraft [PDF]
, 2008 This paper presents a comprehensive assessment of small-signal stability for a “more-electric” aircraft power system consisting of a synchronous variable-frequency generator which supplies several power electronic controlled loads via an 18-pulse ...
Griffo, Antonio, Howe, D., Wang, J.B.
core
Design of Transistor Regulated Power Supplies [PDF]
, 1957 A new form of transistor series regulated power supply is presented which permits unusually good performance characteristics to be realized with simple and economical circuitry.
Middlebrook, R. D.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
IEEE Access, 2020 With the wide deployment of advancing metering infrastructure (AMI) in power distribution systems, the quantity of power consumers' electricity data is increasing rapidly and the data also become more and more accurate.
Bo Zhang +9 more
doaj +1 more source