Results 81 to 90 of about 12,615,912 (289)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Magnetic field density analysis in switchgears [PDF]

, 2011
Publisher Copyright: © 2011, European Association for the Development of Renewable Energy, Environment and Power Quality (EA4EPQ). All rights reserved.For many years the evaluation of the electromagnetic field (EMF) generated by transformer substations ...
J. Izagirre, Del Rio, L., J.E. Rodríguez Seco, A.M. Iraolagoitia, Izagirre, J., P. Fernández, J.A. Güemes, Rodríguez-Seco, J. E., Fernández, P., Iraolagoitia, A. M., Güemes, J. A., L. del Rio   +11 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Power UK '86 Power supply and alternative power sources

, 1986
SIGLEAvailable from British Library Document Supply Centre- DSC:6577.150(1986) / BLDSC - British Library Document Supply CentreGBUnited ...
Power Supply Manufacturers Association, London (United Kingdom)
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Source Current Harmonic Cancellation in Distribution System by Using ANFIS Controller [PDF]

E3S Web of Conferences
Ensuring a reliable and stable power supply to consumers is of utmost importance in modern distribution systems. Many power quality issues, such as voltage fluctuations, harmonic distortions, transient events, load forecasting, and voltage sag/swell ...
Chenchireddy Kalagotla, Varma N. Rajasekhar, Lasya Pendem, Paven Kalyan Goud N., Nithin Meegu, Kumarteja Mandadi   +5 more
doaj   +1 more source

The analysis of regulation of power quality as a component of quality of power supply for agricultural consumers

, 2021
The power quality in rural distribution networks is analysed in article. A conclusion about power quality there is much worse, than in cities what affects the efficiency of electrified technological processes is made. Also the basic directions of regulation of power quality in Ukraine - introduction of standards and minimal requirements on power ...
Trunova, I. M., Potykun, N.Yu.
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source