Results 71 to 80 of about 15,342,094 (302)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
POWER UNITS AND POWER SUPPLY SYSTEMS IN UAV
Aviation, 2014 One of the major tasks in the process of designing future unmanned aerial vehicles is the appropriate choice of a propulsion system and a power source. Depending on the role and size of a given UAV, the following engines are used: electric, jet, turbine and piston (combustion). The following paper also analyses the faultiness of UAVs.
Cwojdziński, Leszek, Adamski, Mirosław
openaire +3 more sources
, 2016 Energy storage is one of the most effective measures to overcome the challenges from the massive integration of renewable energy sources (RESs) with high uncertainty. However, there still lacks inexpensive and feasible choices of energy storage for power
Tang, Y +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2014 Over the past two decades, CPES has secured research funding from major industries, such as GE, Rolls-Royce, Boeing, Alstom, ABB, Toyota, Nissan, Raytheon, and MKS, as well as from government agencies including the NSF, DOE, DARPA, ONR, U.S.
Center for Power Electronics Systems +1 more
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
On the Security of Electricity Supply in Power Distribution Systems
, 2018 Security of electricity supply has become a fundamental requirement for modern societies. However, attempts to define and evaluate security of supply have differed from one another.
Duvnjak Zarkovic, Sanja, +5 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Electrical railway power supply systems: Current situation and future trends
, 2017 Railway electrification is experiencing a very important transformation process today. The need of increasing its capacity has evidenced the drawbacks of conventional systems of dealing with the higher power required, whilst maintaining reasonable costs.
L. Abrahamsson +7 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source