Results 141 to 150 of about 37,967,106 (341)
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
With the rapid development of renewable energy, wind-thermal-bundled power transmission by line-commutated converter based high-voltage direct current (LCC-HVDC) systems has been widely developed. The dynamic interaction mechanisms among permanent magnet
Liwen Zheng, Shiying Ma
doaj +1 more source
POWER LINE COMMUNICATION SYSTEM
Power Line Communication System (PLCS) is an emerging technology that utilizes existing electrical power infrastructure for data transmission. Devices can exchange data and access communication via the power grid thanks to its ability to provide communication across power lines.
null Akshay Charpe +2 more
openaire +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Data-driven Transient Stability Assessment Using Sparse PMU Sampling and Online Self-check Function
Guozheng Wang +6 more
doaj +1 more source
DC near‐area voltage stability constrained renewable energy integration for regional power grids
With the increasing deployment of renewable energy resources, the scale of DC networks and renewable capacity continues to grow. System security is challenged by the decrease in inertia from traditional synchronous generators.
Hailei He +3 more
doaj +1 more source
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source

