Results 51 to 60 of about 1,934,364 (267)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Research and Discuss on Market model based on Blockchain

E3S Web of Conferences, 2018
Electric power industry is the foundation of national economy and plays a key role in the development of human society. Traditional power industry is monopolized by industry and lacked of market efficiency. In recent years, it is seeking breakthroughs in
Cui-hui Yan, Fang Liu, Chaofan Hu, Hui Cui, Bin Wang   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Physical Mechanism Enabled Neural Network for Power System Dynamic Security Assessment

CSEE Journal of Power and Energy Systems
Data-driven artificial intelligence technologies have emerged as increasingly fascinating tools for assessing power system security. However, their inherent mechanism of inexplicability and unreliability now limits their scalability in power systems.
Guozheng Wang, Jianbo Guo, Shicong Ma, Kui Luo, Xi Zhang, Qinglai Guo, Shixiong Fan, Tiezhu Wang, Weilin Hou   +8 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A Novel Data Driven Model for Voltage Stability Status Prediction and Instability Mitigation

International Transactions on Electrical Energy Systems
An intelligent power system is either a system that is smartly designed from zero to 100, or a system that was not smartly designed but currently uses all its facilities to be smartly operated in different sectors. This paper presents a novel data-driven
F. Kh. Alabbas, M. Khalilifar, S. M. Shahrtash, D. A. Khaburi   +3 more
doaj   +1 more source

A coverage algorithm based on D-S theory for directional sensor networks

International Journal of Distributed Sensor Networks, 2016
In view of the random deployment of directional sensor nodes, this article establishes the directional probability sensing model and proposes a distributed deployment strategy based on D-S theory, which makes the perceived probability of the target ...
JuWei Zhang, Na Li, Ningning Wu, Yu Wang, Jingzhuo Shi   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source