Results 41 to 50 of about 24,778,774 (295)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Design of a delay dependent wide area damping controller using Cyber–Physical Power System architecture

open access: yesEnergy Reports, 2023
With the wide application of information and communication technology in power grids, the integration and collaboration of information networks and physical grid have become an essential feature of the smart grid, constituting a typical power information
Zhenglong Sun, Jingbo Zhao, Hao Long
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Improved system operations with high penetration of wind power : a dialog between academia and industry - Ireland [PDF]

open access: yes, 2010
Panel session submission for the IEEE Power and Energy Society (PES) 2010 General Meeting, July 25-29 2010, Minneapolis, MinnesotaThis is a submission to a panel session at the 2010 IEEE PES General Meeting. It discusses effective collaboration between
Power, Michael   +4 more
core   +1 more source

Iterative Energy-Efficient Stable Matching Approach for Context-Aware Resource Allocation in D2D Communications

open access: yesIEEE Access, 2016
Energy efficiency (EE) is critical to fully achieve the huge potentials of device-to-device (D2D) communications with limited battery capacity. In this paper, we consider the two-stage EE optimization problem, which consists of a joint spectrum and power
Zhenyu Zhou   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A Distributed Frequency Regulation Method for Multi-Area Power System Considering Optimization of Communication Structure

open access: yes, 2022
Nowadays, the influences of the communication structure on the frequency regulation performance in a multi-area power system are barely studied. In this paper, a decentralized frequency regulation method for a multi-area power system considering ...
Dongyin Zhang   +7 more
core   +1 more source

Design of Smart Home System Based on Power Line Communication Technology and Wireless Sensor Networks

open access: yesChemical Engineering Transactions, 2016
Based on power line communication technology, research of smart home system-wide power line developed. Combined with high speed power line data communication system based on low-voltage distribution network, set Internet access and intelligent home ...
X.P. Song
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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