Results 91 to 100 of about 1,270,734 (264)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Transformer partial discharge fault diagnosis based on improved adaptive local iterative filtering‐bidirectional long short‐term memory

open access: yesIET Electric Power Applications
Insulation deterioration, which is mainly caused by partial discharge (PD) occurring inside power transformers, is one of the prime reasons to cause transformer faults.
Haikun Shang   +4 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Low-Carbon and Optimized Dispatching of Regional Integrated Energy Systems, Taking into Account the Uncertainties of Wind–Solar Power and Dynamic Hydrogen Prices

open access: yesEnergies
Integrated energy systems are central to advancing efficient energy utilization and low-carbon transformation. In the current context, the inherent variability of high-penetration renewable sources (e.g., wind and solar) and the volatility of multi ...
Zihao Huang   +3 more
doaj   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Subsequent commutation failure suppression strategy of hybrid cascaded HVDC system based on coordinated control of CEC and VDCOL

open access: yesIET Energy Systems Integration
The inverter side of hybrid cascaded HVDC adopts the structure of Modular Multilevel Converter (MMC) in series with Line Commutated Converter (LCC). The complete system amalgamates the advantages of LCC with MMC, but it also makes the interaction process
He Wang   +4 more
doaj   +1 more source

The Impact of the Shunt Reactor(s) Location on Offshore Wind Farm Power Export System on Zero-Missing Phenomenon and Switching Overvoltages—The Case of a Polish Power System

open access: yesEnergies
The observed development of offshore wind farms has resulted in an increasing presence of long extra-high voltage cables, with lengths ranging from 10 to 200 km. These cable lines are compensated for by a shunt reactor(s).
Piotr Rzepka   +5 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Bi-level stochastic optimization for load aggregator participating in energy and reserve markets based on conditional value at risk

open access: yesInternational Journal of Electrical Power & Energy Systems
The integration of large-scale renewable energy into the power system imposes higher demands on the flexible regulation capability of the new power system, urgently necessitating the exploration of the regulatory potential of load-side resources.
Rijun Wang   +6 more
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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