Results 91 to 100 of about 1,329,000 (269)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A review on evaluation and improvement methods for commutation failure resistance ability in multi-infeed direct current system

电力工程技术
The evaluation and improvement methods for commutation failure resistance ability in multi-infeed direct current (MIDC) system are of great significance for testing commutation failure characteristics, addressing assessment challenges, and applying ...
Yechun XIN, Taoyu HUANG, Tuo WANG, Yupeng HE, Xiaoluo GAN, Guoqing LI   +5 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Rethinking Frequency Control in Power Systems

CoRR
Frequency control in power systems is implemented in a hierarchical structure traditionally known as primary frequency control (PFC), secondary frequency control (SFC) and tertiary control reserve (TCR) and, some jurisdictions, include time error control (TEC) as well.
Taulant Kerci, Angel Vaca, Andrew Groom, Julia Matevosyan, Federico Milano 0001   +4 more
openaire   +2 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

A cloud-edge collaborative optimization control strategy for voltage in distribution networks with PV stations

International Journal of Electrical Power & Energy Systems
With the continuous expansion of the power system scale and the continuous development of the power network, the traditional power system management and optimization methods face many challenges.
Guoqing Li, Wei Wang, Dan Pang, Zhipeng Wang, Weixian Tan, Zhenhao Wang, Jinming Ge   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Transformer partial discharge fault diagnosis based on improved adaptive local iterative filtering‐bidirectional long short‐term memory

IET Electric Power Applications
Insulation deterioration, which is mainly caused by partial discharge (PD) occurring inside power transformers, is one of the prime reasons to cause transformer faults.
Haikun Shang, Zixuan Zhao, Ranzhe Zhang, Zhiming Wang, Jiawen Li   +4 more
doaj   +1 more source

Levelized Cost of Electricity for Electric Vehicle Charging in Off-Grid Solar-Powered Microgrid: A Practical Case Study

Energies
The number of electric vehicles is constantly increasing in Europe and around the world. Providing a reliable charging infrastructure for the se vehicles is a major challenge for distribution grid operators.
Nizam Halawi, Dirk Westermann, Steffen Schlegel, Klaus Joas   +3 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source