Results 91 to 100 of about 30,475,499 (311)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Active distance protection schemes for asymmetrical faults of renewable energy stations transmission line

International Journal of Electrical Power & Energy Systems
The limited fault current amplitude and uncertain phase of inverter-interfaced renewable energy stations (IIRES) lead to the risk of malfunction of traditional distance protection.
Yitian Cai, Wenping Qin, Zhilong Zhu, Ruipeng Lu, Kai Zhao, Zheng Yan   +5 more
doaj   +1 more source

Wave power generation and its feasibility in Hong Kong

, 2009
The 8th International Conference on Advances in Power System Control, Operation and Management (APSCOM 2009), Hong Kong, China, 8-11 November 2009. In Proceedings of the 8th International Conference on Advances in Power System Control, Operation and ...
Jiangui Li, K.T. Chau, Chau, KT, Li, J, Li, W, Xiaodong Zhang, Zhang, X, Wenlong Li   +7 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

An Advanced Control System for Wind/Diesel Power Systems

, 1996
International audienceIn this paper an advanced control system for the optimal operation and management of medium-sized autonomous wind-diesel power systems is presented.
Karagounis, Vaggelis, Halliday, Jim, Dutton, Geoff, Kariniotakis, Georges, Nogaret, Eric, Hatziargyriou, Nikos, Androutsos, Aris, Papathanassiou, Stavros, Lopes, Joao Abel Peças, Papadopoulos, Michael, Stavrakakis, Georges, Gatopoulos, John   +11 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Fine-Grained Modeling and Coordinated Scheduling of Source-Load With Energy-Intensive Electro-Fused Magnesium Loads

IEEE Access
With the rising adoption of renewable energy sources worldwide, the uncertainty within electrical power systems is amplifying, leading to rising challenges in wind power assimilation and operational costs.
Yibo Wang, Zikang Yang, Xudong Zhao, Hongdan Liu, Dongzhe Wang, Chuang Liu   +5 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source