Results 51 to 60 of about 1,291,460 (264)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An Efficient Probabilistic Approach Based on Area Grey Incidence Decision Making for Optimal Distributed Generation Planning

IEEE Access, 2019
The increase in the scale of distribution networks significantly reduces the efficiency of intelligent planning for distributed generation (DG). To improve the efficiency of intelligent DG planning and avoid the impact of uncertainty concerning renewable
Dawei Huang, Hongwei Li, Guowei Cai, Nantian Huang, Na Yu, Zheng Huang   +5 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Power grid fault handling plan matching method based on a hybrid neural network

Frontiers in Energy Research
A matching method based on a hybrid neural network is proposed to improve the accuracy of online matching for a power grid fault handling plan. First, the ERNIE 3.0 encoding and double-pointer decoding module are used to replace the generative model in ...
Dajun Xiao, Xialing Xu, Bo Zhang, Yue Zhang, Lianfei Shan, Tao Liu, Xin Li, Yongtian Qiao, Tao Jiang, Yu Wang   +9 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Power control system

, 2012
Oppgaven omhandler å realisere et automasjonssystem med brukergrensesnitt, for energibalansering og regulering av energiproduksjon ved en vindturbinpark, kombinert med et pumpekraftverk. Kraftverkene er via en lukket forsyningssløyfe tilkoblet en by, som til enhver tid skal forsynes med den energimengde som etterspørres.
Kolgrov, Frode, Sandberg, Christian, Grøterud, Erlend, Fjelltun, Lars O., Numme, Peder   +4 more
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Power Systems Control Architecture [PDF]

, 2005
A diagram provided in the report depicts the complexity of the power systems control architecture used by the national power structure. It shows the structural hierarchy and the relationship of the each system to those other systems interconnected to it.
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Adaptive Understanding Framework and Key Technology of Power Grid Fault Disposal Information

Zhongguo dianli
In order to improve the response capacity of power grid fault disposal, an adaptive understanding framework of fault disposal information is proposed. The framework is based on the constructed multi-task collaborative understanding model and the fault ...
Bo TIAN, Yue ZHANG, Fei MENG, Lianfei SHAN, Haiyang GAO, Kun TIAN, Yongtian QIAO   +6 more
doaj   +1 more source