Results 41 to 50 of about 22,917,971 (308)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Wind Power Generation Hardware-in-loop Simulation System Based on Rapid Control Prototype Technology

, 2020
: In order to improve the efficiency and effectiveness in the design and testing process of the wind power generation MPPT controller, a rapid control prototype (RCP) system based on the LabVIEW FPGA platform is proposed. The real-time simulation model
Wu, Aihua, Zhao, Buhui, Mao, Jingfeng, Shen, Haiqun, Zhang, Xudong   +4 more
core   +1 more source

Power System Day-Ahead and Intra-Day Optimal Scheduling Considering Flexible Coordination of Steel Production and Energy Storage

Energies
In order to cope with the challenge of large-scale integration of renewable energy to the balance of power supply and demand, and give full play to the potential of flexible regulation of iron and steel enterprises, a source load coordination ...
Yibo Wang, Lifeng Zhu, Yuan Fang, Jianing Zhou, Chuang Liu   +4 more
doaj   +1 more source

Research on Improved Fault Current Analysis Method for Flexible Direct Current Power Grid Considering Alternating Current Feed

Frontiers in Energy Research, 2021
Flexible direct current (DC) grid can realize large-scale renewable energy, wide-area coordinated complementation, and reliable power transmission. It is an important development that can be used to support high-voltage and large-capacity flexible DC ...
Yinfeng Sun, Xin Xiong, Zhenhao Wang, Guoqing Li, Xueguang Wu, Xueguang Wu, Weiru Wang   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Demonstration of converter control interactions in MMC-HVDC systems [PDF]

, 2022
Although the control of modular multi-level converters (MMCs) in high-voltage direct-current (HVDC) networks has become a mature subject these days, the potential for adverse interactions between different converter controls remains an under-researched ...
Oluwole D. Adeuyi, Parker, Max, Salvatore D’Arco, Sheng Wang, Stephen Finney, D'Arco, Salvatore, Cirio, Diego, Adeuyi, Oluwole D., Wenlong Ming, Andrea Pitto, Iñigo Azpiri, D’Arco, Salvatore, Parker, Max Alexander, Adeuyi, Oluwole Daniel, Salvador Ceballos, Ceballos, Salvador J., Finney, Stephen Jon, Chen, Jinlei, Pitto, Andrea, Ming, Wenlong, Jinlei Chen, Wang, Sheng, Ugalde-Loo, Carlos Ernesto, Ugalde Loo, Carlos E., Diego Cirio, Finney, Stephen, Max Parker, Ceballos, Salvador, Azpiri, Iñigo, Carlos E. Ugalde-Loo, Ugalde-Loo, Carlos E.   +30 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Fine-Grained Modeling and Coordinated Scheduling of Source-Load With Energy-Intensive Electro-Fused Magnesium Loads

IEEE Access
With the rising adoption of renewable energy sources worldwide, the uncertainty within electrical power systems is amplifying, leading to rising challenges in wind power assimilation and operational costs.
Yibo Wang, Zikang Yang, Xudong Zhao, Hongdan Liu, Dongzhe Wang, Chuang Liu   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source