Results 31 to 40 of about 258,437 (269)

Bi-Level Optimal Dispatch of Regional Water–Energy Nexus System Considering Flexible Regulation Potential of Seawater Desalination Plants

Energies
The continuous increase in the penetration rate of renewable energy has posed severe challenges to the flexibility of power systems, especially in coastal and island areas where local power supply is insufficient while electricity demand keeps growing ...
Yibo Wang, Zhongxu Zhou, Yuan Fang, Jianing Zhou, Chuang Liu   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Power System Day-Ahead and Intra-Day Optimal Scheduling Considering Flexible Coordination of Steel Production and Energy Storage

Energies
In order to cope with the challenge of large-scale integration of renewable energy to the balance of power supply and demand, and give full play to the potential of flexible regulation of iron and steel enterprises, a source load coordination ...
Yibo Wang, Lifeng Zhu, Yuan Fang, Jianing Zhou, Chuang Liu   +4 more
doaj   +1 more source

Research on Improved Fault Current Analysis Method for Flexible Direct Current Power Grid Considering Alternating Current Feed

Frontiers in Energy Research, 2021
Flexible direct current (DC) grid can realize large-scale renewable energy, wide-area coordinated complementation, and reliable power transmission. It is an important development that can be used to support high-voltage and large-capacity flexible DC ...
Yinfeng Sun, Xin Xiong, Zhenhao Wang, Guoqing Li, Xueguang Wu, Xueguang Wu, Weiru Wang   +6 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Operator Learning for Power Systems Simulation

CoRR
Time domain simulation, i.e., modeling the system's evolution over time, is a crucial tool for studying and enhancing power system stability and dynamic performance. However, these simulations become computationally intractable for renewable-penetrated grids, due to the small simulation time step required to capture renewable energy resources' ultra ...
Matthew Schlegel, Matthew E. Taylor, Mostafa Farrokhabadi   +2 more
openaire   +3 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Fine-Grained Modeling and Coordinated Scheduling of Source-Load With Energy-Intensive Electro-Fused Magnesium Loads

IEEE Access
With the rising adoption of renewable energy sources worldwide, the uncertainty within electrical power systems is amplifying, leading to rising challenges in wind power assimilation and operational costs.
Yibo Wang, Zikang Yang, Xudong Zhao, Hongdan Liu, Dongzhe Wang, Chuang Liu   +5 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source