Results 21 to 30 of about 1,720,290 (233)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Modeling and simulation of data communication networks using SARA [PDF]

, 1985
The selection of an appropriate simulation language can have a profound impact on the success of a simulation study. The available options range from domain-specific simulation languages to general-purpose programming languages. These languages are often
Razouk, Rami R.
core   +1 more source

Simulating the Smart Grid

, 2013
Major challenges for the transition of power systems do not only tackle power electronics but also communication technology, power market economy and user acceptance studies. Simulation is an important research method therein, as it helps to avoid costly
Elmenreich, Wilfried, Pöchacker, Manfred, Sobe, Anita   +2 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Simulation of dynamic load effect on power system frequency [PDF]

, 2013
This thesis addresses the impact of dynamic load on power system frequency. Rapid dynamic load variations will bring significant impact to the power system in terms of frequency. The thesis is based on three-phase dynamic load (composite based). The
Azizan, Abdul Rahman
core  

Operation and control of a current source converter series tapping of an LCC-HVDC link for integration of offshore wind power plants [PDF]

, 2016
This work presents a series tapping station for integrating Offshore Wind Power Plants (OWPP) into a (Line Commutated Converter High Voltage Direct Current) LCC-HVDC transmission system.
Galceran Arellano, Samuel, Gomis Bellmunt, Oriol, Prieto Araujo, Eduardo, Sau Bassols, Joan   +3 more
core   +2 more sources

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

A Social Spider Algorithm for Solving the Non-convex Economic Load Dispatch Problem [PDF]

, 2015
Economic Load Dispatch (ELD) is one of the essential components in power system control and operation. Although conventional ELD formulation can be solved using mathematical programming techniques, modern power system introduces new models of the power ...
Li, Victor O. K., Yu, James J. Q.
core   +2 more sources

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Design and control of a bidirectional wireless charging system using GaN devices [PDF]

, 2019
Most of the existing wireless power transfer system works in unidirectional with one-direction control signals. This paper presents a bidirectional wireless charging system with duplex communication method, which is not only able to achieve the two-way ...
Gu, Bowen, Ji, Bing, Pickert, Volker, Wang, Xiang, Wu, Haimeng   +4 more
core   +2 more sources