Results 141 to 150 of about 710 (260)

Feedback control of excitability and high K+ induced epileptiform bursts in male rat hippocampal slices with a photocaged adenosine A1 receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Adenosine is a potent regulator of neurotransmission and neuronal excitability, through activation of Gi coupled adenosine A1 receptors (A1Rs). Adenosine has gained interest as an anticonvulsant because of its endogenous involvement in ending seizure activity, but peripheral side effects require local application.
Erine Craey, Marijke Vergaelen, Serge Van Calenbergh, Jeroen Spanoghe, Evelien Carrette, Kristl Vonck, Paul Boon, Wytse J. Wadman, Robrecht Raedt   +8 more
wiley   +1 more source

Targeted nanocarriers integrating photodynamic and photothermal therapy: a paradigm shift in rheumatoid arthritis treatment. [PDF]

Nanoscale Adv
Priya S, Sharma D, Jain KK, Chutani S, Singhvi G.   +4 more
europepmc   +1 more source

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease

Epilepsia, EarlyView.
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa, Laura Bellingacci, Jacopo Canonichesi, Valentina Imperatore, Anna Aurora Taddei, Luis Zafra‐Puerta, Nerea Iglesias‐Cabeza, Paolo Prontera, Andrea Mancini, Massimiliano Di Filippo, Alessandro Tozzi, Katiuscia Martinello, Marta Barzasi, Fabrizio Gardoni, Marina P. Sánchez, José M. Serratosa, Lucilla Parnetti, Miriam Sciaccaluga   +17 more
wiley   +1 more source

Artificial Optimizer Algorithm for Power System Stabilizer design problem and multidisciplinary engineering applications. [PDF]

Heliyon
Singh N, Kaur M, Houssein EH.
europepmc   +1 more source

Stabilization of low-cost phase change materials for thermal energy storage applications. [PDF]

iScience, 2023
Akamo DO, Kumar N, Li Y, Pekol C, Li K, Goswami M, Hirschey J, LaClair TJ, Keffer DJ, Rios O, Gluesenkamp KR.   +10 more
europepmc   +1 more source

Preliminary Clustering: Exploring the Interplay of Burnout, Stress, Turnover, Psychological Flexibility and Distress in a French Nurse Sample

Journal of Advanced Nursing, EarlyView.
ABSTRACT Objective To identify latent profiles of hospital nurses based on the combination of occupational demands, psychological symptoms and psychological flexibility. Examine how these profiles relate to job turnover intentions. Design Cross‐sectional online survey.
Marie Charlotte Mollet, Oulmann Zerhouni, Corinne Isnard Bagnis, Lucia Romo   +3 more
wiley   +1 more source

Highly reconfigurable neuronlike conductive networks through nanophase structure engineering. [PDF]

Nat Commun
Zhong W, Zhao H, Yao B, Li Z, Zhou S, Wang Z, Geng Y, Sun W, Fu J.   +8 more
europepmc   +1 more source

Developing giant plasma membrane vesicles from Leishmania cells to investigate the role of membrane proteins in photodynamic inactivation

Photochemistry and Photobiology, EarlyView.
In this study, we developed giant plasma membrane vesicles (GPMVs) from Leishmania amazonensis promastigote membranes to investigate the role of protein‐embedded membranes in methylene blue (MB) photooxidation. Upon MB photoactivation in model lipid membranes (giant unilamellar vesicles, GUVs), a distinct photooxidation effect was observed, marked by ...
Maressa D. F. de Souza, Pietro Ciancaglini, Rosangela Itri, Martha S. Ribeiro   +3 more
wiley   +1 more source

Optimization of Zein-Casein-Hyaluronic Acid Nanoparticles Obtained by Nanoprecipitation Using Design of Experiments (DoE). [PDF]

ACS Omega
Babinski TP, Padilha Lorenzett AK, Ziebarth J, Lima VA, Mainardes RM.   +4 more
europepmc   +1 more source

Time‐series multi‐omics analysis of micronutrient stress in Sorghum bicolor reveals iron and zinc crosstalk and regulatory network conservation

Plant Biology, EarlyView.
Overlap between Fe and Zn responsive gene regulatory networks (GRNs) were found, indicative of micronutrient crosstalk, and conservation of root and leaf GRNs and genes suggests strong constraint on homeostasis networks in plants. Abstract Micronutrient stress impacts growth, biomass production, and grain yield in crops.
A. Mishra, A. Bhat, S. Kumari, R. Sharma, J. Braynen, D. Tadesse, S. El Alaoui, S. Seaver, N. Grosjean, D. Ware, M. Xie, T. Paape   +11 more
wiley   +1 more source