Results 61 to 70 of about 246,265 (278)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Issues in integrating existing multi-agent systems for power engineering applications [PDF]
, 2005 Multi-agent systems (MAS) have proven to be an effective platform for diagnostic and condition monitoring applications in the power industry. For example, a multi-agent system architecture, entitled condition monitoring multi-agent system (COMMAS ...
Catterson, V.M. +2 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
High VoltageExcessively high temperatures inside a power transformer can accelerate the ageing rate and even cause unplanned outages. Accurately estimating the hot‐spot temperature (HST) of a power transformer is important for regulating the load and ensuring long ...
Yuan Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Distributed acoustic sensing monitoring of overburden fractures in coal mine goaf
地质科技通报Objective As socioeconomic development advances, challenges associated with coal mining beneath structures such as buildings, water bodies, and railways have intensified markedly.
Kai CAO +6 more
doaj +1 more source
Investigating inter-turn fault in transformer using TTR and FRA [PDF]
, 2019 Transformers are one of the significant elements in the power system network. The Transformer function is to step up and down the voltages. When the transformer operating in high load, it exposes to failures.
Abdulrazzaq Al-Iedani, Ali Salman
core
A Modelling Tool for Distribution Networks to Demonstrate Smart Grid Solutions [PDF]
, 2014 The increased deployment of low carbon technologies in power distribution networks, particularly at the distribution level, is expected to cause significant problems to network operation unless existing networks are appropriately adapted and actively ...
Bentley, Edward +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source