Results 131 to 140 of about 6,908,000 (315)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Electromagnetic safety enhancing in railway electric supply systems

open access: yesE3S Web of Conferences, 2018
The methods of simulation modeling of traction power supply systems is developed, allowing analyzing the electromagnetic safety conditions in complex traction power networks equipped with sucking transformers.
Buyakova Natal’ya   +3 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Saturation current protection apparatus for saturable core transformers Patent [PDF]

open access: yes, 1970
Magnetic current regulator for saturable core ...
Schwarz, F. C.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

El mantenimiento a los transformadores de potencia; su análisis en el caso de una Central termoeléctrica cubana;Maintenance of power transformers; its analysis in the case of a Cuban thermal power station

open access: yesRevista Científica de Ingeniería Energética, 2011
El presente artículo está dirigido a la exposición del proceso de mantenimiento a los transformadores de potencia, el mantenimiento preventivo, las normativas de mantenimiento y las pruebas a transformadores de potencia, el mantenimiento predictivo, el ...
Jorge Juan Montané - García,et al.
doaj  

Robust Wireless Power Transfer for EVs by Self-Oscillating Controlled Inverters and Identical Single-Coil Transmitting and Receiving Pads

open access: yesEnergies
Inductive wireless power transfer (IWPT) with stable output power and high efficiency is a major challenge for charging electric vehicles (EVs). This paper, for the first time, develops a robust IWPT system using a circular pad (CP) and double-D pad (DDP)
Alireza Eikani   +5 more
doaj   +1 more source

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