Results 81 to 90 of about 2,381,180 (298)
El giro populista de El Salvador: la presidencia de Nayib Bukele (2019-2023)
ConfluenzeThis article analyzes the first presidency of Nayib Bukele who, in 2019, won the presidential elections in El Salvador, putting an end to the political alternation of the two large parties that emerged from the Chapultepec peace agreements in 1992.
Nicolas Balutet
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Paying for What You Get—Restitution Recovery for Breach of Contract [PDF]
, 2018 This article begins with a brief discussion of restitution as a remedy for breach of contract under the Restatement (Second) of Contracts. It then discusses the changes the Restatement of Restitution adopts and the reasons for the changes.
Powers, Jean Fleming
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Bulletin of Kharkiv National University of Internal AffairsThe article notes that limiting the discretionary powers of law enforcement agencies through the implementation of legislative provisions which would detail and set the limits for the application of these powers is seen as one of the primary tasks for ...
O. A. Prysiazhniuk
doaj +1 more source
Сибирское юридическое обозрение, 2019 The article presents an analysis of the legal status of the Maslikhat Chairman and Maslikhat Secretary under the laws of the Republic of Kazakhstan. In the framework of this study, the features of the role and position of these positions in the structure
Z. Z. Tasybaeva
doaj +1 more source
, 2010 For a graph G, its rth power is constructed by placing an edge between two vertices if they are within distance r of each other. In this note we study the amount of edges added to a graph by taking its rth power.
Pokrovskiy, Alexey
core +2 more sources