Results 81 to 90 of about 2,056,400 (324)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Sharp weighted Sobolev trace inequalities and fractional powers of the Laplacian

open access: yes, 2019
We establish a family of sharp Sobolev trace inequalities involving the $W^{k,2}(\mathbb{R}_+^{n+1},y^a)$-norm. These inequalities are closely related to the realization of fractional powers of the Laplacian on $\mathbb{R}^n=\partial\mathbb{R}_+^{n+1 ...
Case, Jeffrey S.
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Les Pouvoirs dans la ville

open access: yesL'Espace Politique, 2009
Introductory article of the issue 8 (2009-2) of the journal L’Espace politique entitled "Powers in the City"
Catherine Fournet-Guérin   +1 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

An analogue of the Milnor conjecture for the de Rham-Witt complex in characteristic 2

open access: yesForum of Mathematics, Sigma
We describe the modulo $2$ de Rham-Witt complex of a field of characteristic $2$ , in terms of the powers of the augmentation ideal of the $\mathbb {Z}/2$ -geometric fixed points of real topological restriction homology ${\mathrm ...
Emanuele Dotto
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

CONVERGENCE OF POWERS OF CONTROLLABLE INTUITIONISTIC FUZZY MATRICES

open access: yesICTACT Journal on Communication Technology, 2016
Convergences of powers of controllable intuitionistic fuzzy matrices have been stud¬ied. It is shown that they oscillate with period equal to 2, in general.
Riyaz Ahmad Padder, P. Murugadas
doaj  

Home - About - Disclaimer - Privacy