Results 131 to 140 of about 164 (161)

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). I. Treatments in preclinical and early clinical development

Epilepsia, EarlyView.
Abstract Over the last 34 years, the Eilat Conference on New Antiepileptic Drugs and Devices has provided an interactive forum for stakeholders to discuss investigational and recently licensed treatments for seizures and epilepsy. The Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII) took place in Madrid, Spain, on May 3 ...
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Predicting levetiracetam neuropsychiatric adverse effects using graph‐theoretical electroencephalographic network metrics in drug‐naive focal epilepsy: A multicenter longitudinal study

Epilepsia, EarlyView.
Abstract Objective Levetiracetam (LEV) is an antiseizure medication approved for focal and generalized epilepsy. Despite its efficacy, neuropsychiatric adverse effects (NP‐AEs) may lead to treatment discontinuation. Quantitative electroencephalographic (qEEG) graph‐theoretical analysis has emerged as a valuable tool for identifying neurophysiological ...
Marco Sferruzzi, Lorenzo Ricci, Margherita Anna Grazia Matarrese, Francesca Izzi, Fabio Placidi, Biagio Maria Sancetta, Emanuele Cerulli Irelli, Patrizia Pulitano, Vincenzo Di Lazzaro, Mario Tombini, Giovanni Assenza   +10 more
wiley   +1 more source

Creativity and its link to epilepsy

Epilepsia Open, EarlyView.
Abstract Creative thinking represents one of our highest‐order cognitive processes, involving multiple cortical structures and an intricate interplay between several cortical and subcortical networks. It results in novel ideas that translate to useful products or concepts. The evolutionary purpose of creativity is therefore apparent, as it advances our
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Design Internal Forces of Non‐Dissipative Members in CBFs With Regular and Irregular Brace Configurations

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Steel Concentrically Braced Frames (CBFs) are widely used in seismic regions, with chevron and split‐X configurations commonly adopted for their structural efficiency and architectural flexibility. Although extensive research has been carried out on these systems, the effectiveness of the formulations available in the literature for estimating
Melina Bosco, Pier Paolo Rossi
wiley   +1 more source

An Intensity Measure‐Based Methodology for Ground Motion Orientation in Seismic Structural Assessment

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT In current dynamic time history assessment protocols, ground motion recordings are mostly oriented along fixed sensor directions. Consequently, the orientation of the principal resultant of rupture energy, which may control the maximum structural demand, remains undefined, precluding consistent correlation with physically detrimental ...
Santiago Londono‐Lopez, Raffaele Cucuzza, Fabrizio Mollaioli, Giuseppe Carlo Marano, Marco Domaneschi   +4 more
wiley   +1 more source

Using a wearable electrocardiogram (ECG) patch adapted for 7‐day monitoring in the horse

Equine Veterinary Journal, EarlyView.
Abstract Background Arrhythmias can cause poor performance and sudden death in horses. Long‐term (>24 h) electrocardiogram (ECG) monitoring has been used to identify arrhythmias in humans and is superior to short‐term monitoring for transient arrhythmia detection. Televet is the current equine gold‐standard ECG device. The Cardea SOLO™ (CS) is a single‐
Tatiana Delecave Dias, Robert G. Hauser, Kendall Blanchard Cleary, Sian Durward‐Akhurst   +3 more
wiley   +1 more source

Combustion Properties of Timber in Historic Structures: Case Study of the São Pedro de Alcântara Chapel Fire

Fire and Materials, EarlyView.
ABSTRACT Timber plays a fundamental role in the fire performance of historic building components, where ageing and environmental exposure can markedly influence its physical and chemical properties. This study presents an experimental investigation of the fire behaviour of Ocotea sp.
João Vitor Lopes Ferreira, Ana Lucia de Souza Ventapane, Bruno Polycarpo Palmerim Dias, Simone Pereira da Silva Ribeiro, Alexandre Landesmann   +4 more
wiley   +1 more source

Performing history, negotiating patriarchy: Actressing as gendered labor and the fragmentation of womanhood in Chinese historical costume drama

Feminist Anthropology, EarlyView.
Abstract Gender inequality remains widespread in the film and television production industry, yet it is seldom examined in relation to backstage working environments. This article integrates on‐screen and off‐screen perspectives to investigate the working lives of Chinese actresses.
Yajie Li, Yuhao Ding
wiley   +1 more source

Revisiting International Student Mobility Under New Geopolitics: Stratification, Conditionality, and Uncertainty

Future in Educational Research, EarlyView.
ABSTRACT In the 21st century, the governance of international student mobility has undergone a fundamental transformation, driven primarily by securitization, geoeconomic competition, and domestic political pressures that conventional market‐based frameworks such as the push‐pull model and human capital theory cannot adequately explain.
Shibao Guo, Zhongrui Wang
wiley   +1 more source