Results 81 to 90 of about 36,908 (243)

Left ventricular diastolic dysfunction worsens prognosis in patients with heart failure due to dilated cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1183-1193, April 2025.
Abstract Aims The prognostic significance of left ventricular (LV) diastolic dysfunction (LVDD) severity in patients with dilated cardiomyopathy (DCM) remains uncertain. This study aimed to evaluate the association of LVDD severity and elevated left atrial pressure (eLAP) with patient outcomes in stable, non‐acutely decompensated patients with DCM ...
Mateusz Winiarczyk, Ewa Dziewięcka, Sylwia Wiśniowska‐Śmiałek, Agnieszka Stępień, Katarzyna Graczyk, Agata Leśniak‐Sobelga, Marta Hlawaty, Jakub Woźniak, Maryia Savitskaya, Katarzyna Holcman, Magdalena Kostkiewicz, Piotr Podolec, Paweł Rubiś   +12 more
wiley   +1 more source

Efficacy of low-dose primaquine plus artemether-lumefantrine or dihydroartemisinin-piperaquine for radical cure of Plasmodium vivax in the Solomon Islands: a randomised clinical trial

Frontiers in Malaria
BackgroundPrimaquine (PQ) remains the only 8-aminoquinoline endorsed by the WHO for treatment of latent Plasmodium vivax liver-stage parasites. PQ is a prodrug, with metabolism and therapeutic activity influenced by inherent human CYP2D6 polymorphisms ...
Robert James, Robert James, Thomas Obadia, Thomas Obadia, Lyndes Wini, Albino Bobogare, Sarah Charnaud, Sarah Charnaud, Shazia Ruybal-Pesántez, Shazia Ruybal-Pesántez, Caitlin Bourke, Caitlin Bourke, Jacob E. Munro, Jacob E. Munro, Brioni R. Moore, Brioni R. Moore, Brioni R. Moore, Madhu Page-Sharp, Madhu Page-Sharp, Laurens Manning, Laurens Manning, Urijah Liligeto, Sophie G. Zaloumis, J. Kevin Baird, J. Kevin Baird, Harin Karunajeewa, Ivo Mueller, Ivo Mueller   +27 more
doaj   +1 more source

Design of a Multi‐Complex Disturbance Generator Using Virtual Instrumentation for Power Quality Monitoring Research

Energy Science &Engineering, EarlyView.
A real‐time power quality disturbance generator is developed using virtual instrumentation based on LabVIEW and NI MyDAQ. The system generates IEEE‐standard PQ events with controllable noise and harmonics. Measurement uncertainty analysis confirms its reliability for realistic testing of Power Quality Disturbance detection and classification algorithms.
Abdullah Saud, Adil Usman, Muhammad Umar Khan, Sumair Aziz, Muhammad Faisal Nadeem Khan, Muhammad Akmal   +5 more
wiley   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

Extraction of Antimicrobial Peptides From Fava Bean Protein Hydrolyzate by Phosphorylated Biochar

Food Safety and Health, EarlyView.
Antimicrobial peptides were extracted by functional biochar in one step. The enriched peptides demonstrated significantly enhanced antibacterial activity. ABSTRACT The extraction of antimicrobial peptides (AMPs) from plant proteins remains challenging due to their low abundance, structural diversity, and the need for mild, efficient, and selective ...
Xiang‐Yu Huang, Hao‐Ran Liu, Rong Guo, Li Ding, Li Wen, Xu‐Feng Wang, Zhou Xu, Yun‐Hui Cheng, Mao‐Long Chen   +8 more
wiley   +1 more source

Macrophage extracellular vesicles deliver Mef2d proteins to aggravate Bacteroides fragilis pathogenicity in type 2 diabetes arterial calcification

Interdisciplinary Medicine, EarlyView.
Bacteroides fragilis is associated with type 2 diabetes (T2D) arterial calcification and can be activated by macrophage‐derived extracellular vesicles (EVs). BF takes up EVs via receptor‐mediated endocytosis, and activation is induced by EV‐derived Mef2d, thereby inhibiting ArsR family transcriptional regulator transcription.
Cong Chen, Rong He, Jirong Luo, Zhengfeng Liang, Qunwen Pan, Shuangquan Liu, Jingsong Cao   +6 more
wiley   +1 more source

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati, Giulia Trinchera, Alice Casoni, Alessandra Pecorelli, Mascia Benedusi, Maria Chiara Pietrogrande, Giuseppe Valacchi   +6 more
wiley   +1 more source

Verification of False Reactivity in HIV Rapid Diagnostic Tests and Its Translation Into the Three Tests Algorithm in Cameroon

Journal of Clinical Laboratory Analysis, EarlyView.
Verification study enabled the detection of HIV false reactivity ranging from 0‐4% across rapid diagnostic tests. A reliable three‐tests algorithm ranked First Response HIV 1‐2‐0 Card, First Response HIV1+2/Syphilis Combo or STANDARD Q as suitable test 1 to mitigate false positive events. As countries move toward HIV elimination, implementing the three‐
Rogers Ajeh Awoh, Désiré Takou, Isidore Oscar Bienvenu Etogo Ondigui, Roger Onana, Etienne Kembou, Collins Chenwi, Daniel Mabongo, Grace Beloumou Angong, Laetitia Bissai, Aude Christelle Ka'e, Alex Durand Nka, Ezechiel Ngoufack Jagni Semengue, Nadine Fainguem, Daniele Simnoue, Florine Tsimene, Sandrine Djupsa, Jaurès Metambou, Aurelie Kengne, Arlette Messeh, Gilbert Tchatchoua, Naomi‐Karell Etame, Michel Tommo, Krystel Zam Nnomo, Edith Temgoua, Basil Yaba, Gregory Edie Halle Ekane, Carlo‐Federico Perno, Vittorio Colizzi, Nicaise Ndembi, Diaby Ousmane, Joelle Bouba Pamen, Alexis Ndjolo, Celine Lastrucci, Joseph Fokam, Malachie Manouada   +34 more
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source

Reward processing in children with affective dysregulation

JCPP Advances, EarlyView.
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner, Francisca Giller, Nathalie Holz, Anna Kaiser, Christine Igel, Sarah Hohmann, Manfred Döpfner, Veit Roessner, Christian Beste, Tobias Banaschewski, Daniel Brandeis, on behalf ofthe ADOPT Consortium   +11 more
wiley   +1 more source