Results 121 to 130 of about 2,622,623 (241)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Revue des Sciences de la SantéLa poliomyélite demeure un problème de santé publique malgré les progrès liés à la vaccination, en raison de la persistance des poliovirus dérivés de souches vaccinales, particulièrement dans les zones à faible couverture vaccinale.
Jimmy LIGAMBA BALE +7 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Étude de la prévalence du surpoids au sein d'une population d'enfants atteints de déficience intellectuelle [PDF]
, 2014 Introduction : La prévalence du surpoids en France s’est stabilisée sur la période 2000-2010. Chez l'enfant atteint de déficience intellectuelle, elle semble beaucoup plus importante mais sous-évaluée.
Cadet, Thomas
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Health Research in AfricaIntroduction. Despite chronic kidney disease (CKD) being a major problem in Type 2 diabetes mellitus (T2DM), only a few studies have addressed CKD among patients with T2DM in Cameroon. The aim of our study is to determine the clinical and epidemiological
Teuwafeu Denis Georges +8 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
La dyspareunie chez les adolescentes : prévalence, caractéristiques et corrélats biopsychosociaux [PDF]
, 2010 Problématique: Les études épidémiologiques récentes suggèrent que la prévalence de la dyspareunie est de 12% à 21 % chez les femmes adultes et que son incidence augmente. Alors que les données cliniques suggèrent que la dyspareunie débute fréquemment à l'
Landry, Tina
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Revue des Sciences de la SantéCette recherche vise à analyser la prévalence et les caractéristiques des infections urinaires (IU) chez les personnes vivant avec le VIH (PVVIH), ainsi qu'à identifier les facteurs sociodémographiques, cliniques et comportementaux qui y sont associés ...
Liévin TIBASIMA DHESSA +3 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Prévalence et dépistage du burnout dans la population belge [PDF]
, 2011 The aim of the study was to estimate the prevalence of burnout among Belgian workers through the identification of burnout cases within the practices of general practitioners (GP) and the health surveillance carried out by occupational health physicians (
Braeckman, Lutgart +7 more
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