Results 61 to 70 of about 1,055,290 (365)

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez, Anna Felip‐Badia, Marina Caballero‐Bellon, Nazaret Sanchez‐Sierra, Alicia Castañeda, Moira Garraus, Maite Gorostegui, Margarida Simão‐Rafael, Juan Pablo Muñoz, Marta Perez‐Somarriba, Salvador Mañe, Mariana Cecilia Planells, Sara Perez‐Jaume, Jaume Mora   +13 more
wiley   +1 more source

Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters [PDF]

Microbial Cell Factories, 2010
Abstract The temperature inducible expression system, based on the pL and/or pR phage lambda promoters regulated by the thermolabile cI857 repressor has been widely use to produce recombinant proteins in prokariotic cells. In this expression system, induction of heterologous protein is achieved by increasing the culture temperature, generally
Trujillo-Roldán Mauricio A, Ramírez Octavio T, Pérez Néstor O, Caspeta Luis, Valdez-Cruz Norma A   +4 more
openaire   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Plasmatic Levels of Cytokines and Quality of Life among Elderly Individuals with Dizziness

International Archives of Otorhinolaryngology
Introduction Few studies have investigated the relationship between cytokines and dizziness in elderly individuals.
Gislaine da Silva Moreira, Luciana Lozza de Moraes Marchiori, Daiane Soares de Almeida Ciquinato, Glória de Moraes Marchiori, Licia Sayuri Tanaka Okamura, Braulio Henrique Magnani Branco, Regina Célia Poli-Frederico   +6 more
doaj   +1 more source

A Kano model-based demand analysis and perceived barriers of pulmonary rehabilitation interventions for patients with chronic obstructive pulmonary disease in China.

PLoS ONE, 2023
BackgroundPulmonary rehabilitation (PR) has been recognized to be an effective therapy for chronic obstructive pulmonary disease (COPD). However, in China, the application of PR interventions is still less promoted.
Xinmeng Yao, Jinmei Li, Jialu He, Qinzhun Zhang, Yi Yu, Yinan He, Jinghua Wu, Weihong Tang, Chengyin Ye   +8 more
doaj   +1 more source

EMPLOYEE MOTIVATION AND PUBLIC SECTOR FRAUD: EVIDENCE FROM KWARA STATE, NIGERIA [PDF]

, 2015
This study examines the relationship between fraud and employee motivation in the Kwara State public sector with a view to ascertain what will happen to fraud occurrence if good salary, allowances and perquisites, effective working hours, conducive ...
ABIOLA, W. O., ADEBAYO, S. A., OLANIYI, T. A., SAAD, T.   +3 more
core   +2 more sources

The role of" Special Economic Zones"(SEZ) of the ICT industry for the development of the creative industry in Kazakhstan [PDF]

, 2022
Nowadays, the creative industry in Kazakhstan is a young direction of the economy. The government supports this industry with tax benefits, the provision of infrastructure, as well as the creation of Special Economic Zones (SEZ) in large megacities of ...
Gazzola P., Nurbatsin A.
core   +1 more source

Participatory approaches in the context of research into workplace health promotion to improve physical activity levels and reduce sedentary behaviour among office-based workers: protocol for a scoping review

BMJ Open, 2021
Introduction Physical activity (PA) workplace health promotion (WHP) interventions have traditionally used a top-down research approach where end-users are considered as passive subjects.

semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source