Results 101 to 110 of about 4,441,566 (351)

China’s Strategic Misjudgement on Myanmar

open access: yesJournal of Current Southeast Asian Affairs, 2012
Yun Sun argues that China’s policy failures on Myanmar in 2011 are rooted in several strategic post-election misjudgements. Following President Thein Sein’s inauguration in March 2011, the Sino–Myanmar relationship was initially boosted by the ...
Yun SUN
doaj  

Replacing BPA: Structural Substitutes BPAF Binding to the Progesterone Receptor Elevates Breast Cancer Risk

open access: yesAdvanced Science, EarlyView.
This study demonstrates that bisphenol analogues, particularly BPAF, bind to progesterone receptor, promoting breast cancer cell proliferation, migration, and mammary tumor growth, indicating that bisphenol A substitutes may pose equal or greater health risks.
Xiaotong Ji   +8 more
wiley   +1 more source

The Vexing Strategic Tug-of-War over Naypyidaw: ASEAN’s View of the Sino–Burmese Ties

open access: yesJournal of Current Southeast Asian Affairs, 2012
This article argues that ASEAN’s policy toward Myanmar has been predominantly responsive, dictated by China’s activism in the region. It posits three arguments: First, that the release of political prisoners, including Aung San Suu Kyi, may have been a ...
Pavin Chachavalpongpun
doaj  

Single‐Nucleus RNA Sequencing Reveals Mid‐Gestational Neurodevelopment Features in the Superior Temporal Plane from Fetuses with Nonsyndromic Cleft Lip and Palate

open access: yesAdvanced Science, EarlyView.
Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong   +19 more
wiley   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

open access: yesAdvanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv   +8 more
wiley   +1 more source

Epidemiological characteristics of holoprosencephaly in China, 2007-2014: A retrospective study based on the national birth defects surveillance system.

open access: yesPLoS ONE, 2019
ObjectiveTo describe the epidemiology of holoprosencephaly (HPE) in China with special reference to prevalence and associated anomalies.MethodsData were abstracted from the Chinese Birth Defects Monitoring Network for the period 2007-2014.
Ling Yi   +10 more
doaj   +1 more source

Stimuli‐Responsive CuFeTe2 Nanosheets for Amplified Cuproptosis/Ferroptosis in Triple‐Negative Breast Cancer Therapy

open access: yesAdvanced Science, EarlyView.
Dual‐stimuli‐responsive CuFeTe2 nanosheets (CFT) induce cuproptosis/ferroptosis via TME‐responsive Fe2⁺/Cu2⁺ release and NIR‐II photothermal effects, amplifying ROS and depleting HSP70/ATP to trigger ICD and immune activation, while ensuring biocompatible renal clearance for TNBC therapy.
Molin Liu   +14 more
wiley   +1 more source

Grundzüge der wirtschaftlichen Entwicklung und ihre ordnungspolitischen Leitbilder in der VR China seit 1949 [PDF]

open access: yes, 2014
Der Beitrag zeichnet die zentralen Entwicklungs- und Wachstumslinien der chinesischen Volkswirtschaft seit Gründung der VR China nach und stellt die in verschiedenen Perioden verfolgten ordnungspolitisch-institutionellen Leitbilder dar.
Taube, Markus
core  

Tumor‐Derived CDC37 Inhibits Antigen Cross‐Presentation in Dendritic Cells and Impairs Anti‐Tumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Extracellular vesicle (EV)‐packaged CDC37 are released from TMBhiCTLlo breast cancer cells with high CDC37 expression, and internalized into endo/phagosomes of dendritic cells (DCs). Within these compartments, CDC37 locked HSP90–antigen complex, preventing antigen release into the cytosol.
Ruxin Wang   +10 more
wiley   +1 more source

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