Results 171 to 180 of about 740,415 (313)

Gabpα‐Pparγ Complex Determines Glycolytic Capacity and Lactic Acid Homeostasis in Brown Fat

open access: yesAdvanced Science, EarlyView.
This study identifies the Gabpα–Pparγ complex as a key transcriptional regulator that couples glycolysis to lactate‐driven thermogenesis in brown adipose tissue by directly activating Eno1 transcription. ‌Competitive disruption of this interaction impairs lactate metabolism and thermogenic capacity.
Zhihan Wang   +22 more
wiley   +1 more source

Epidemiological survey on clonorchiasis sinensis in Yangxin County of Hubei Province of PR China

open access: green, 1997
S. Chen   +6 more
openalex   +1 more source

Multifunctional Tailoring of Fertilizer Composites Directly Derived From Phosphate Rock

open access: yesAdvanced Science, EarlyView.
A novel phosphorus‑sulfur mixed acid with urea (PSU) activation system converts low‑grade phosphate rock (LPR) into multifunctional fertilizer composites (MFCs). MFCs feature porous structures, high nutrient‑activation efficiency, superior slow‑release, and enhanced crop growth, offering a sustainable solution for integrated nutrient management and ...
Zenglian Qi   +13 more
wiley   +1 more source

Correction: UHRF1-mediated epigenetic reprogramming regulates glycolysis to promote progression of B-cell acute lymphoblastic leukemia. [PDF]

open access: yesCell Death Dis
Huang Y   +12 more
europepmc   +1 more source

Ultra‐Sensitive Dual‐Resonator Graphene Pressure Sensor with Temperature Self‐Compensation

open access: yesAdvanced Science, EarlyView.
This work presents a graphene resonator sensor based on a dual‐cavity interferometric scheme that achieves high sensitivity to pressure variations. Its lightweight and compact design enables drone‐based field experiments, underscoring the promise of graphene optomechanical devices for portable and scalable sensing applications.
Zhen Wan   +7 more
wiley   +1 more source

Nursing Future Horizon: Simultaneous Continual Nursing Model and Homemade Dialogue Tool for Controlling Cardiac Function and Blood Pressure in Hypertensive Heart Diseases

open access: yesPatient Preference and Adherence
Hai Ou Yang,1 Aiping Wang,2 Haihua Hu,3 Yue Li4 1Beijing Tongren Hospital Affiliated to Capital Medical University, PR. China Internal Medicine Department 100730, Beijing, People’s Republic of China; 2Beijing Tongren Hospital Affiliated to Capital ...
Yang HO, Wang A, Hu H, Li Y
doaj  

A Scalable Method for Cavity‐Enhanced Solid‐State Quantum Sensors

open access: yesAdvanced Science, EarlyView.
Photoluminescent color centres in diamond and hexagon boron nitride are powerful nanoscale solid‐state quantum sensors. Methods for integrating them into macroscopic structures that improve their sensitivity are highly sought after. This study demonstrates a low‐cost and scalable method for the fabrication of quantum sensor‐doped thin‐film cavities ...
Daniel J. Tibben   +5 more
wiley   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

open access: yesAdvanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

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