Results 181 to 190 of about 4,441,566 (351)

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao   +13 more
wiley   +1 more source

Hump‐Shaped Relationship Between Microbial Carbon Use‐Efficiency and Soil Organic Carbon in Alpine Grasslands

open access: yesAdvanced Science, EarlyView.
On the Qinghai–Tibetan Plateau, microbial carbon use efficiency (CUE) peaks at intermediate soil organic carbon levels and declines thereafter. In carbon‐rich soils, the formation of stable mineral‐associated organic carbon is decoupled from microbial CUE.
Yuting Wang   +8 more
wiley   +1 more source

Physical Interpretation of Diffractive Optical Networks for High‐Dimensional Vortex Mode Sorting

open access: yesAdvanced Science, EarlyView.
The first layer‐resolved physical interpretation of diffractive optical networks trained for high‐dimensional vortex mode sorting is presented, revealing transformation division phenomena linked to saturated performance as layer numbers increase. This analysis reconciles physical theorems with network operations, enabling physics‐driven design of ...
Ruitao Wu   +7 more
wiley   +1 more source

Nursing Future Horizon: Simultaneous Continual Nursing Model and Homemade Dialogue Tool for Controlling Cardiac Function and Blood Pressure in Hypertensive Heart Diseases

open access: yesPatient Preference and Adherence
Hai Ou Yang,1 Aiping Wang,2 Haihua Hu,3 Yue Li4 1Beijing Tongren Hospital Affiliated to Capital Medical University, PR. China Internal Medicine Department 100730, Beijing, People’s Republic of China; 2Beijing Tongren Hospital Affiliated to Capital ...
Yang HO, Wang A, Hu H, Li Y
doaj  

Oxyanions stabilized low-coordinated nickel species for efficient and durable nucleophilic electrooxidation. [PDF]

open access: yesNat Commun
Liu X   +8 more
europepmc   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

open access: yesAdvanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu   +13 more
wiley   +1 more source

Additional file 1 of Genetic and clinical landscape of ER + /PR- breast cancer in China

open access: gold, 2023
Danian Dai   +5 more
openalex   +1 more source

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