Results 21 to 30 of about 745,731 (317)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source
Atomic Size Misfit for Electrocatalytic Small Molecule Activation
Advanced Functional Materials, EarlyView.This review explores the application and mechanisms of atomic size misfit in catalysis for small molecule activation, focusing on how structural defects and electronic properties can effectively lower the energy barriers of chemical bonds in molecules like H2O, CO2, and N2.
Ping Hong +3 more
wiley +1 more source
Inner Mongolia's Mongol Nomads [PDF]
, 1988 Film of 59 mins.Filmed in about 1988 in East Ujimqin Banner, Xilingol League, Inner Mongolia Autonomous Region, PR China. This ethnographic film focuses on nadam, food preparation including dairy properties, yurts, a wedding, and ...
Zhang, Wei
core
Advanced Functional Materials, EarlyView.A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao +11 more
wiley +1 more source
Global Health Research and PolicyBackground China has implemented the priority review (PR) program and flexible registration requirements for new drugs with significant clinical value since 2016 to accelerate drug access.
Xingyue Zhu, Jinsui Zhang
doaj +1 more source
Ethnodemographic specifications of Xinjiang (P.R. of China) [PDF]
Zbornik Radova: Geografski Fakultet Univerziteta u Beogradu, 2019 The paper examines ethnic, demographic, cultural and linguistic aspects of China's Xinjiang Province. It analyzes regional specifications and through cause-and-effect explains historical process of formation of different ethnicities and nations, their ...
Grbović Vladan
doaj
Emergent Spin‐Glass Behavior in an Iron(II)‐Based Metal–Organic Framework Glass
Advanced Functional Materials, EarlyView.A one‐pot, solvent‐free synthesis yields an Fe2+‐based metal‐organic framework (MOF) glass featuring a continuous random network structure. The material exhibits spin‐glass freezing at 14 K, driven by topological‐disorder and short‐range magnetic frustration, showcasing the potential of MOF glasses as a plattform for cooperative magnetic phenomena in ...
Chinmoy Das +8 more
wiley +1 more source
Comparative Efficacy of Various Sources and Rates of Phosphate Rocks to Oil Palm Seedlings [PDF]
, 1997 Phosphate Rocks (PR) from various geographical locations are being imported into the Malaysian market mainly from Algeria, North Carolina (USA), Tunisia, China etc. PR vary widely in their physical, chemical and mineralogical properties. Consequently,
Lubis, Muhammad Edwin Syahputra
core
How visas shape and make visible the geopolitical architecture of the planet
, 2016 The aim of the present study is to provide a picture for geopolitical globalization: the role of all world countries together with their contribution towards globalization is highlighted.
Ausloos, Marcel +4 more
core +1 more source