Results 71 to 80 of about 745,731 (317)

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Factors influencing the energy saving potential of suburban dwellings in Jiangsu Province, China

Scientific Reports
As environmental concerns continue to rise, scholars worldwide are increasingly focusing on energy efficiency in rural energy use. This study explores the energy efficiency potential of rural households in China, aiming to identify the key factors that ...
Gang Yao, Chao Xie, Renyong Zhang, Yuqian Hong, Zhongcheng Duan   +4 more
doaj   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Factors Influencing Compliance with Pulmonary Rehabilitation in Patients with Stable COPD: a Cross Sectional Study

International Journal of COPD
Xiao Xia,1,2 Kun Xia,1 Xiaoyan Yao,1 Jianjun Song,1 Yanyi Liu,1,3 Xiaohong Liu,1,2 Haoxiang Zhang,1,2 Guangxi Li1 1Guanganmen Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 2Graduate School of China Academy of ...
Xia X, Xia K, Yao X, Song J, Liu Y, Liu X, Zhang H, Li G   +7 more
doaj  

China’s Strategic Misjudgement on Myanmar

Journal of Current Southeast Asian Affairs, 2012
Yun Sun argues that China’s policy failures on Myanmar in 2011 are rooted in several strategic post-election misjudgements. Following President Thein Sein’s inauguration in March 2011, the Sino–Myanmar relationship was initially boosted by the ...
Yun SUN
doaj  

A comparison of breastfeeding among Han, Uygur and other ethnic groups in Xinjiang, PR China [PDF]

, 2006
Fenglian Xu, Colin Binns, Guli Nazi, Lin Shi, Yun Zhao, Andy Lee   +5 more
openalex   +1 more source

TRADITIONAL TIBETAN SONGS, INSTRUMENTS, AND A DMANGS GLU SINGER IN MDO BA (DUOWA) TOWN, MTSHO SNGON (QINGHAI) PROVINCE, PR CHINA

, 2023
Chos skyong skyabs ཆོས་སྐྱོང་སྐྱབས།
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

The Vexing Strategic Tug-of-War over Naypyidaw: ASEAN’s View of the Sino–Burmese Ties

Journal of Current Southeast Asian Affairs, 2012
This article argues that ASEAN’s policy toward Myanmar has been predominantly responsive, dictated by China’s activism in the region. It posits three arguments: First, that the release of political prisoners, including Aung San Suu Kyi, may have been a ...
Pavin Chachavalpongpun
doaj  

Characterization of a novel reassortment Tibet orbivirus isolated from Culicoides spp. in Yunnan, PR China. [PDF]

J Gen Virol, 2021
Ren N, Wang X, Liang M, Tian S, Ochieng C, Zhao L, Huang D, Xia Q, Yuan Z, Xia H.   +9 more
europepmc   +1 more source