Results 41 to 50 of about 391,775 (314)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Explore on screening COX-2 inhibitors from the essential oil of Solanum lyratum Thunb. By molecular docking and molecular dynamics simulation

Heliyon
This study aimed to investigate Solanum lyratum Thunb. with respect to the potential ingredients with anti-inflammatory activity from its essential oil by silico study. To this regard, the essential oil of Solanum lyratum Thunb.
Hanyang Xiao, Yan Gui, Xianfei Li, Wen Dai, Chuanhua Feng, Gang Li, Jiangnan Luo   +6 more
doaj   +1 more source

Dynamics of a nonlocal SIR epidemic model with free boundaries

Franklin Open, 2023
This paper is devoted to a nonlocal SIR type epidemic model, with free boundary denoting the expanding front. We aim to examine the full information about the dynamical behaviors of the involved disease that caused by the nonlocal diffusion and growing ...
Jia-Feng Cao, Jie Wang, Meng Zhao, Yu-Xia Feng   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Factors associated with functional disability in older adults with cancer treated at reference outpatient clinics in the state of Mato Grosso, Brazil

Revista Brasileira de Epidemiologia, 2022
: Objective: To analyze factors associated with functional disability in older adults with cancer treated at reference outpatient clinics in the state of Mato Grosso, Brazil. Methods: This is a cross-sectional study of 463 older adults aged 60 years or
Juliana Fernandes Cabral, Noemi Dreyer Galvão, Amanda Cristina de Souza Andrade, Ageo Mário Cândido da Silva   +3 more
doaj   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Work program of the discipline "Psychology of advertising and PR" [PDF]

, 2022
Мета навчальної дисципліни - забезпечити формування професійної компетентності студентів щодо психологічного забезпечення діяльності у сфері реклами та PR (Паблік Рілейшнз). Завдання курсу: ознайомити студентів з цілями, функціями, різновидами реклами
Цюман, Тетяна Петрівна
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Magnetic nanoparticles-based targeted drug delivery system in tumor pain management

SLAS Technology
Background: the precise management of tumor-related pain is a critical challenge in improving the quality of life (QoL) of cancer patients. This study aimed to develop a magnetic nanoparticle-based transdermal drug delivery system (MNPs-TDDS) using green
Xiaoli Lv, Fei Wang, Xiaomei Liu, Ting Xu, Xiaofeng Zhou   +4 more
doaj   +1 more source

Pd Supported on Pr-Rich Cerium–Zirconium–Praseodymium Mixed Oxides for Propane and CO Oxidation

Catalysts, 2022
The activity of emission control catalysts must be improved in urban mode at low temperatures. One possible way is to tailor the metal-support interaction between platinum group metals (PGMs) and ceria to stabilize small clusters or single atoms, optimizing the utilization of costly PGMs.
Simon Fahed, Rémy Pointecouteau, Mimoun Aouine, Antoinette Boreave, Sonia Gil, Philippe Bazin, Alain Demourgues, Marco Daturi, Philippe Vernoux   +8 more
openaire   +2 more sources