Results 71 to 80 of about 391,775 (314)

Lifetime measurements in Pr-134 and chirality in nuclei

, 2006
Lifetimes of exited states in Pr-134 were measured be means of the recoil distance Dopplershift and Doppler-shift attenuation techniques. The experiments were performed at IReS, Strasbourg using the EUROBALL IV spectrometer, in conjunction with the inner
De Angelis, G., Marginean N., Petrache, C., Dewald A., Moeller O., Gadea, A., Bazzacco, D., Balabanski D. L., Frauendorf, S., Tonev D., Brant S., Zhong Q., Zhong, Q., Pejovic P., LUNARDI, SANTO, Petkov P., Fitzler, A., Curien D., Frauendorf S., Zell K. O., De Angelis G., Fitzler A., Zhang, Y. H., Bednarczyk, P., Dewald, A., Napoli D. R., LENZI, SILVIA MONICA, Balabanski, D. L., Napoli, D. R., Tonev, D., Lenzi, S., Petrache C., Bazzacco D., Marginean, N., Pejovic, P., Brant, S., Zhang, Jing-Ye, Petkov, P., Moeller, O., Gadea A., Zhang Jing Ye, Zhang Y. H., Zell, K. O., Lunardi, S., Bednarczyk P., Curien, D.   +45 more
core   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Multicriteria assessment of the response capability of urban emergency shelters: A case study in Beijing

Natural Hazards Research
Urban emergency shelters are pivotal for safety, with effective evaluation criteria enabling decision-makers to identify strengths and weaknesses, facilitating targeted enhancements.
Yiting Xu, Wei Wang, Hong Chen, Minhao Qu   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Distribution laws of landslides and theirs influencing factors in the Qiaojia segment of Jinsha River, China

Natural Hazards Research
The landslide disaster database is a prerequisite for regional landslide disaster research, and summarizing and analyzing the distribution pattern and influencing factors of landslide disasters is of great significance for carrying out the susceptibility
Liu Chaohai, Renmao Yuan, Wang Ying
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Apoptotic body-encapsulated nanoparticles regulate inflammation through macrophage polarization mediated by lactic acid

Annals of Medicine
Background Inflammation has been implicated in numerous diseases. The treatment of inflammation-related diseases is a significant global burden. Recent studies have found that lactic acid and its signalling pathway can inhibit inflammatory responses ...
Hai-Cun Zhou, Jian-Ping Long, Tao Yang, Zhi-Hen Yan, Wen-Wen Yu, Chang-An Guo, Xiao-Qin Liang, Xin-Yan Yan   +7 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Factors associated with perceived quality of life in older adults: ELSI-Brazil

Revista de Saúde Pública, 2018
OBJECTIVE To identify factors associated with perceived quality of life in a representative national sample of the population aged 50 or over. METHODS Data from 7,651 participants of the baseline ELSI-Brazil (Brazilian Longitudinal Study of Aging ...
Anita Liberalesso Neri, Flávia Silva Arbex Borim, Arlete Portella Fontes, Dóris Firmino Rabello, Meire Cachioni, Samila Sathler Tavares Batistoni, Mônica Sanches Yassuda, Paulo Roberto Borges de Souza Júnior, Fabiola Bof de Andrade, Maria Fernanda Lima-Costa   +9 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source