Results 31 to 40 of about 101,816 (263)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Comparative performance analysis of vtr and ctr in digital video advertising

open access: yesХабаршы Журналистика сериясы, 2019
The PR market is gaining momentum every day, and specialists in this field use new technological solutions for greater productivity. Modern PR in practice gradually goes online with the target audience. But PR and marketing as a science do not keep pace
Шынгысовa Н.   +1 more
doaj   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Atomistic understanding of the variable nano-hardness of C-plane sapphire considering the crystal anisotropy

open access: yesJournal of Materials Research and Technology
Nanoindentation test method is widely used to measure the material hardness, which is a standard test and the effect of measurement error is limited. However, the measured results of the nano-hardness for the same plane of single crystal materials, such ...
Tian Qiu   +7 more
doaj   +1 more source

Participatory Research Methods – Choice Points in the Research Process

open access: yesJournal of Participatory Research Methods, 2020
Participatory research (PR) encompasses research designs, methods, and frameworks that use systematic inquiry in direct collaboration with those affected by an issue being studied for the purpose of action or change.
Lisa M. Vaughn, Farrah Jacquez
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

INTERNAL PR AS PART OF CORPORATE CULTURE

open access: yesВестник университета, 2019
The identification of mechanisms for the implementation of public relations and the selection of effective internal PR tools can affect the organization’s management.
O. Goryacheva
doaj   +1 more source

Peculiarities of Teaching PR in Public Administration at Higher Education Institutions

open access: yesЦифрова платформа: інформаційні технології в соціокультурній сфері, 2022
The purpose of the article is to analyze the peculiarities of teaching PR in public administration to students who master advertising and public relations. The research methodology is based on the principles of scientific and pedagogical research and
Олена Морозова
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Effects of pulmonary rehabilitation in survivors of severe acute respiratory syndrome coronavirus 2. Role of vaccination

open access: yesMonaldi Archives for Chest Disease, 2023
Survivors of severe COVID-19 requiring hospital admission may suffer from short- and long-term sequelae, including disability and reduced physical performance.
Matteo Vigna   +5 more
doaj   +1 more source

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