Results 141 to 150 of about 239,484 (351)

The Practicality of Practical Inference [PDF]

, 2021
In Intention, Anscombe says that practical reasoning is practical, not by virtue of its content, but rather by virtue of its form. But in her later essay ‘Practical Inference’, she seems to take this back, claiming instead that (1) the practicality of ...
Small, Will
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Analgesic Efficacy, Practicality and Safety of Inhaled Methoxyflurane Versus Standard Analgesic Treatment for Acute Trauma Pain in the Emergency Setting: A Randomised, Open-Label, Active-Controlled, Multicentre Trial in Italy (MEDITA)

Advances in Therapy, 2019
Inhaled low-dose methoxyflurane is approved in Europe for emergency relief of moderate-to-severe trauma-related pain in adults, but data versus active comparators are sparse.
S. Mercadante, A. Voza, S. Serra, G. Ruggiano, G. Carpinteri, G. Gangitano, F. Intelligente, E. Bonafede, Antonella Sblendido, A. Farina, A. Soldi, A. Fabbri   +11 more
semanticscholar   +1 more source

Validity And Practicality of PjBL-Based Teaching Materials Environmental Pollution For Physics Phase E [PDF]

The purpose of this research is to test the validity and practicality of the project-based learning teaching materials that have been developed.. This research is research and development (R&D) with a model-4D development model.
Rahmadini, Fadhilla, Yulia Sari, Silvi, Gusnedi, Gusnedi, Darvina, Yenni   +3 more
core   +2 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Highly Sensitive Amperometric Sensor for the Determination of Glucose at Histidine Stabilized Copper Nanospheres Decorated Multi-Walled Carbon Nanotubes

International Journal of Electrochemical Science, 2016
Uniform sized copper nanospheres (CuNSs) were deposited at functionalised multiwalled carbon nanotubes (f-MWCNTs) modified glassy carbon electrode (GCE) through a simple electrochemical method.
Shen-Ming Chen, Rajkumar Devasenathipathy, Sea-Fue Wang, Karuppasamy Kohilarani   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

PRACTICALITY OF SCIENCE TEACHERS BOOK WITH THE THEMES OF BLOOD FLUID USING LEARNING OF INTEGRATED CONNECTED TYPE 21ST CENTURY LEARNING [PDF]

, 2019
Teachers book is a guide for teachers in carrying out learning as well as guidelines for the use of student books. One way to find out the quality of the teachers book that was developed was by the practicality test.
Tri Anidya Putri, Ratnawulan and Syafriani, Riza Helfira   +2 more
core   +1 more source