Results 111 to 120 of about 8,812,920 (310)

A Meta-analysis on the Effectiveness of Trauma-informed Practice [PDF]

, 2020
This study looked at past research on trauma informed practice to analyze its effectiveness.. There is sufficient research portraying the helpfulness of the trauma-informed approach; however, there is little research on whether it is effective as a ...
Barajas, Lesley, Martinez, Gabriela
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Evidence Cafés and Practitioner Cafés supported by online resources: A route to innovative training in practice based approaches [PDF]

, 2017
Current radical changes in the Police service internationally and in England and Wales are being driven by movements to adopt an Evidence-Based Practice (EBP) approach to policing.
Adams, Anne, Clough, Gill, Halford, Eric
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

General practice prestige: understanding medical students’ perceptions – a repeated cross-sectional study

BMC Medical Education
Introduction A global shortage of general practitioners (GPs) is partly due to the limited number of medical students interested in working in the field. Prestige is one of several factors influencing choice of medical specialty.
Ulrike Spary-Kainz, Laura Plotho, Andrea Siebenhofer, Anna Mangge, Stephanie Poggenburg, Alexander Avian   +5 more
doaj   +1 more source

Collaborative Instruction for Information Retrieval and Appraisal Skills in Evidence-Based Practice Models for Dental Hygiene Students. [PDF]

, 2017
Objectives: 1. Collaborate with VCU Dental Hygiene Program faculty to develop and evaluate a model of evidence-based practice (EBP) for students in didactic and clinical settings. 2. Describe how a course was modified to emphasize evidence-based practice.
Lubker, Irene M, Pellegrini, Joan M.
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Experiencing COVID-19 Through the Patient Lens to Promote Empathy: Pilot Testing a Virtual Reality Learning Opportunity

Journal of Patient Experience
Understanding the patient's experience with COVID-19 was essential to providing high-quality, person-centered care during the pandemic. Having empathy or being able to understand and respond to the patient's experience may lead to improved outcomes for ...
Heather Thomson RN, PhD, Lisa Di Prospero MRTT, BSc, MSc, Sarah Xiao RN, PhD, Laurie Legere BA, BPR, Tamara Harth BA, MLIS, Laura Rashleigh RN, MScN, Maria Parzanese RN, MN, Lorraine Graves, Kyle Wilcocks PhD(c), Fahad Alam MD, FRCPC, MHSc   +9 more
doaj   +1 more source